SCHEMBL922233

SCHEMBL922233

Nc1nc(F)ccc1C(=O)NCc1ccc(Oc2cccc(I)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GALR3 O60755 1/20 0.41
NR2F2 P24468 1/20 0.41
MAPK14 Q16539 4/20 0.41
PTGER4 P35408 2/20 0.40
CYP3A4 P08684 2/20 0.40
HTT P42858 2/20 0.40
LMNA P02545 1/20 0.40
MMP13 P45452 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
PTGER2 P43116 1/20 0.40
LIPG Q9Y5X9 1/20 0.40
HPGD P15428 2/20 0.39
KLKB1 P03952 2/20 0.39
KLK1 P06870 1/20 0.39
HTR2C P28335 1/20 0.39
HTR2B P41595 1/20 0.39
MAPK8 P45983 1/20 0.39
ALDH1A1 P00352 1/20 0.39
GAA P10253 1/20 0.39
ATM Q13315 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921571 0.93 HPGD (0.46) MAPK14MMP13HPGDALDH1A1
SCHEMBL920924 0.90 MAPK14 (0.45) MAPK14MMP13HPGDALDH1A1
SCHEMBL919925 0.90 HTR2C (0.49) GALR3NR2F2MAPK14PTGER4CYP3A4
SCHEMBL920472 0.89 LIPG (0.44) GALR3NR2F2MAPK14PTGER4CYP3A4
SCHEMBL921469 0.88 MAPK14 (0.52) GALR3NR2F2MAPK14PTGER4CYP3A4
SCHEMBL922765 0.88 MAPK14 (0.47) GALR3NR2F2MAPK14PTGER4CYP3A4
SCHEMBL920468 0.88 KLKB1 (0.49) GALR3NR2F2MAPK14PTGER4CYP3A4
SCHEMBL920524 0.88 KDM4E (0.50) MMP13SMN1; SMN2HPGDALDH1A1
SCHEMBL920047 0.88 HPGD (0.42) GALR3NR2F2MAPK14PTGER4CYP3A4
SCHEMBL921891 0.88 MAPK14 (0.45) GALR3NR2F2MAPK14CYP3A4HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 GALR3 4520/4885NR2F2 2795/4885MAPK14 905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.