SCHEMBL922765

SCHEMBL922765

Cc1cccc(Oc2ccc(CNC(=O)c3ccc(F)nc3N)cc2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 3/20 0.47
ALDH1A1 P00352 3/20 0.45
KDM4E B2RXH2 2/20 0.45
HPGD P15428 2/20 0.45
HSD17B10 Q99714 1/20 0.45
PTGER4 P35408 1/20 0.44
PPARG P37231 1/20 0.44
PPARD Q03181 1/20 0.44
PPARA Q07869 1/20 0.44
MMP13 P45452 2/20 0.43
KLKB1 P03952 1/20 0.43
ADORA2A P29274 1/20 0.42
ADORA1 P30542 1/20 0.42
LIPG Q9Y5X9 1/20 0.42
MAPK1 P28482 1/20 0.42
GFER P55789 1/20 0.42
HTT P42858 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
MMP2 P08253 1/20 0.42
CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920504 0.93 KDM4E (0.51) ALDH1A1KDM4EHPGDHSD17B10PPARG
SCHEMBL920524 0.90 KDM4E (0.50) ALDH1A1KDM4EHPGDPPARGPPARD
SCHEMBL920433 0.90 MMP13 (0.56) MAPK14ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL920420 0.90 MAPK14 (0.49) MAPK14ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL919925 0.90 HTR2C (0.49) MAPK14PTGER4KLKB1LIPGCYP3A4
SCHEMBL921316 0.89 MAPK14 (0.53) MAPK14ALDH1A1KDM4EHPGDPTGER4
SCHEMBL921982 0.89 MAPK14 (0.44) MAPK14ALDH1A1KDM4EHPGDPPARG
SCHEMBL921469 0.88 MAPK14 (0.52) MAPK14ALDH1A1HPGDPTGER4PPARG
SCHEMBL919487 0.88 KLKB1 (0.46) HPGDKLKB1SMN1; SMN2CYP3A4
SCHEMBL922233 0.88 GALR3 (0.41) MAPK14ALDH1A1HPGDPTGER4MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
WO-2009107764-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS 住友化学株式会社 (JP) 2009-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 MAPK14 905/4885ALDH1A1 2743/4885KDM4E 3657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.