SCHEMBL922430

SCHEMBL922430

CP(=O)(CC=O)OCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
SRC P12931 1/20 0.44
CETP P11597 3/20 0.44
FOLH1 Q04609 1/20 0.42
ALDH1A1 P00352 2/20 0.39
AOX1 Q06278 1/20 0.38
KDM4E B2RXH2 1/20 0.37
MAPK1 P28482 1/20 0.37
MAOB P27338 1/20 0.37
PDPK1 O15530 1/20 0.37
MTOR P42345 1/20 0.37
ALPG P10696 1/20 0.37
PTK2B Q14289 1/20 0.37
IDO1 P14902 1/20 0.36
PKM P14618 1/20 0.36
SRD5A2 P31213 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3624069 0.83 AOX1 (0.50) TSHRSRCCETPFOLH1ALDH1A1
SCHEMBL922111 0.83 RAB9A (0.40) ALDH1A1KDM4EMAOBIDO1
SCHEMBL14439909 0.81 TSHR (0.55) TSHRSRCCETPFOLH1ALDH1A1
SCHEMBL12567320 0.79 TSHR (0.57) TSHRSRCCETPFOLH1ALDH1A1
SCHEMBL13185883 0.79 TSHR (0.57) TSHRSRCCETPFOLH1ALDH1A1
SCHEMBL17170447 0.78 TSHR (0.55) TSHRSRCCETPFOLH1ALDH1A1
SCHEMBL389180 0.77 TSHR (0.63) TSHRSRCCETPFOLH1ALDH1A1
SCHEMBL3367142 0.77 TSHR (0.63) TSHRSRCCETPFOLH1ALDH1A1
SCHEMBL13896611 0.76 TSHR (0.53) TSHRCETPFOLH1ALDH1A1
SCHEMBL26361302 0.76 TSHR (0.53) TSHRSRCCETPFOLH1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2138502-B1 PROCESS FOR PRODUCING PHOSPHORUS-CONTAINING DEHYDROAMINO ACID MEIJI SEIKA PHARMA CO LTD (JP) 2014-02-19 EP disclosed
US-8329935-B2 Process for producing phosphorus-containing dehydroamino acid MEJI SEIKA KAISHA LTD. (JP) 2012-12-11 US disclosed
US-20110009662-A1 PROCESS FOR PRODUCING PHOSPHORUS-CONTAINING DEHYDROAMINO ACID MEIJI SEIKA KAISHA LTD. (JP) 2011-01-13 US disclosed
EP-2138502-A1 PROCESS FOR PRODUCING PHOSPHORUS-CONTAINING DEHYDROAMINO ACID Meiji Seika Kaisha Ltd. (JP) 2009-12-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009662-A1 PROCESS FOR PRODUCING PHOSPHORUS-CONTAINING DEHYDROAMINO ACID AMPD2, AMPD1, AMPD3 TSHR 2147/4885SRC 3364/4885CETP 2989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.