Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | IRS1 | P35568 | 1/20 | 0.46 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.46 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11455802 | 0.84 | ALDH1A1 (0.73) | LMNAALDH1A1HSD17B10TSHRKDM4E | |
| SCHEMBL2517599 | 0.79 | LMNA (0.62) | LMNAALDH1A1HSD17B10TSHRKDM4E | |
| SCHEMBL7156060 | 0.79 | UCHL1 (0.71) | LMNAALDH1A1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL1196550 | 0.79 | CYP4Z1 (0.50) | LMNAALDH1A1HSD17B10TSHRKDM4E | |
| SCHEMBL2519148 | 0.79 | ALDH1A1 (0.58) | LMNAALDH1A1HSD17B10TSHRKDM4E | |
| SCHEMBL6079885 | 0.77 | ALDH1A1 (0.64) | LMNAALDH1A1HSD17B10TSHRKDM4E | |
| SCHEMBL5842450 | 0.76 | HPGD (0.63) | LMNAALDH1A1HSD17B10TSHRKDM4E | |
| SCHEMBL2693160 | 0.76 | ALDH1A1 (0.63) | LMNAALDH1A1HSD17B10TSHRKDM4E | |
| SCHEMBL2665963 | 0.74 | LMNA (0.56) | LMNAALDH1A1HSD17B10TSHRKDM4E | |
| SCHEMBL27513611 | 0.74 | CYP1A2 (0.62) | LMNAALDH1A1HSD17B10TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459026-A | N-phosphonoalkylindole derivatives | FUJI PHOTO FILM CO., LTD. (JP) | 1995-10-17 | — | — | US | disclosed |