Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HMGCR | P04035 | 3/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6916387 | 0.89 | LMNA (0.47) | LMNARECQLALOX5PTGS1PTGS2 | |
| SCHEMBL9224571 | 0.81 | GAA (0.49) | LMNAALOX5MEN1KMT2AHMGCR | |
| SCHEMBL9224042 | 0.81 | GABBR2 (0.47) | LMNAALOX5PTGS1PTGS2MEN1 | |
| SCHEMBL6910755 | 0.80 | GAA (0.49) | LMNARECQLMEN1KMT2AHMGCR | |
| SCHEMBL6915809 | 0.80 | HMGCR (0.38) | LMNARECQLMEN1KMT2AHMGCR | |
| SCHEMBL6918005 | 0.79 | VCAM1 (0.40) | LMNARECQLPTGS1HMGCRGPR55 | |
| SCHEMBL6917719 | 0.75 | GABBR2 (0.52) | ALOX5PTGS1PTGS2HMGCRGPR55 | |
| SCHEMBL9222208 | 0.74 | TNFRSF1A (0.47) | LMNARECQLALOX5PTGS1PTGS2 | |
| SCHEMBL724655 | 0.74 | PTGS1 (0.51) | LMNARECQLALOX5PTGS1PTGS2 | |
| SCHEMBL9225329 | 0.74 | LMNA (0.50) | LMNARECQLALOX5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638084-A1 | SUBSTITUTED PHOSPHONATES, THE PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1995-02-15 | — | — | EP | claimed |
| WO-1994019358-A1 | SUBSTITUTED PHOSPHONATES, THE PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1994-09-01 | — | — | WO | claimed |