Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HMGCR | P04035 | 3/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9225348 | 0.89 | LMNA (0.43) | LMNARECQLALOX5PTGS1PTGS2 | |
| SCHEMBL6917719 | 0.80 | GABBR2 (0.52) | ALOX5PTGS1PTGS2HMGCRGPR55 | |
| SCHEMBL6915809 | 0.79 | HMGCR (0.38) | LMNARECQLKMT2AMEN1HMGCR | |
| SCHEMBL6910755 | 0.79 | GAA (0.49) | LMNARECQLKMT2AMEN1HMGCR | |
| SCHEMBL9222208 | 0.79 | TNFRSF1A (0.47) | LMNARECQLALOX5PTGS1PTGS2 | |
| SCHEMBL6914237 | 0.78 | HMGCR (0.48) | LMNARECQLALOX5PTGS1PTGS2 | |
| SCHEMBL9513470 | 0.78 | HMGCR (0.50) | LMNARECQLKMT2AMEN1HMGCR | |
| SCHEMBL9225329 | 0.78 | LMNA (0.50) | LMNARECQLALOX5PTGS1PTGS2 | |
| SCHEMBL6918409 | 0.78 | VCAM1 (0.45) | LMNARECQLHMGCRGPR55NR1I2 | |
| SCHEMBL6918005 | 0.78 | VCAM1 (0.40) | LMNARECQLPTGS1HMGCRGPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026245-A2 | SUBSTITUTED PHOSPHONATE COMPOUNDS HAVING BONE ANABOLIC ACTIVITY | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | claimed |