SCHEMBL5812554

SCHEMBL5812554

CCOCn1c(-c2ccc(Cl)c(Cl)c2)c(C#N)c(Cl)c1C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CTSS P25774 1/20 0.34
CTSK P43235 1/20 0.34
HPGD P15428 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
SLC6A3 Q01959 1/20 0.33
RXFP1 Q9HBX9 1/20 0.31
AKR1C3 P42330 1/20 0.30
AKR1C2 P52895 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5819704 0.89 CTSS (0.33) CTSSCTSKHPGDMEN1KMT2A
SCHEMBL5812558 0.87 RXFP1 (0.36) HPGDMEN1KMT2ANPSR1RXFP1
SCHEMBL5819964 0.86 MAOA (0.34) HPGDMEN1KMT2ANPSR1RXFP1
SCHEMBL5819960 0.86 KIF11 (0.35) CTSSCTSKRXFP1
SCHEMBL9015141 0.85 RXFP1 (0.35) CTSSCTSKHPGDMEN1KMT2A
SCHEMBL5812533 0.85 ADORA1 (0.33) HPGDRXFP1LMNA
SCHEMBL9225473 0.85 ADORA1 (0.33) HPGDSLC6A3LMNA
SCHEMBL9268665 0.84 KDM4E (0.30)
SCHEMBL9271591 0.83 AR (0.38) HPGDRXFP1AKR1C3AKR1C2
SCHEMBL9390222 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0895839-B1 Arylpyrroles for the protection of wood, wood products and wood structures from insect attack BASF AG (DE) 2006-09-20 EP claimed
EP-0895717-B1 Arylpyrroles for subterranean termite control BASF AG (DE) 2003-05-28 EP claimed
EP-0895717-A1 Arylpyrroles for subterranean termite control American Cyanamid Company (US) 1999-02-10 EP claimed
EP-0895839-A1 Arylpyrroles for the protection of wood, wood products and wood structures from insect attack American Cyanamid Company (US) 1999-02-10 EP claimed
EP-0895839-B1 Arylpyrroles for the protection of wood, wood products and wood structures from insect attack BASF AG (DE) 2006-09-20 EP disclosed
EP-0895717-B1 Arylpyrroles for subterranean termite control BASF AG (DE) 2003-05-28 EP disclosed
US-6077863-A TREATING WOOD OR WOOD PRODUCT OR SOIL SURROUNDED WITH ARYLPYRROLE INSECTICIDE, SPECIALLY TO KILL THE TERMITES AND CARPENTER ANTS AMERICAN CYANAMID COMPANY (US) 2000-06-20 US disclosed
US-6071951-A APPLYING SUBSTITUTED PYRROLE INSECTICIDES TO INFESTED SOILS OR ENVIRONMENTS AMERICAN CYANAMID COMPANY (US) 2000-06-06 US disclosed
EP-0895839-A1 Arylpyrroles for the protection of wood, wood products and wood structures from insect attack American Cyanamid Company (US) 1999-02-10 EP disclosed
EP-0895717-A1 Arylpyrroles for subterranean termite control American Cyanamid Company (US) 1999-02-10 EP disclosed