Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | POLQ | O75417 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL267005 | 0.98 | IDO1 (0.53) | IDO1POLQNPSR1MAOBMAOA | |
| Methylamine SCHEMBL28261812 | 0.96 | IDO1 (0.57) | IDO1POLQNPSR1MAOBMAOA | |
| SCHEMBL12631962 | 0.84 | GABRA1 (0.44) | IDO1POLQNPSR1MAOBMAOA | |
| SCHEMBL12955733 | 0.84 | GABRA1 (0.44) | IDO1POLQNPSR1MAOBMAOA | |
| SCHEMBL16105687 | 0.82 | GABRA1 (0.43) | IDO1POLQNPSR1MAOBMAOA | |
| SCHEMBL327569 | 0.82 | IDO1 (0.52) | IDO1POLQNPSR1MAOBMAOA | |
| SCHEMBL481000 | 0.81 | IDO1 (0.55) | IDO1POLQNPSR1MAOBMAOA | |
| SCHEMBL5415312 | 0.80 | GABRA1 (0.46) | IDO1POLQGABRA1GABRB2AKR1B1 | |
| SCHEMBL21312967 | 0.80 | GABRA1 (0.46) | IDO1POLQNPSR1MAOBMAOA | |
| SCHEMBL11967099 | 0.80 | GABRA1 (0.46) | IDO1POLQNPSR1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 726 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107011133-A | The method that a kind of benzyl position C H keys are direct oxidation into ketone | 中国科学技术大学 | 2017-08-04 | — | — | CN | claimed |
| CN-103382144-B | Alkyl aromatic alpha- halogenation method | UNIV HEBEI SCIENCE & TECH | 2014-09-10 | — | — | CN | claimed |
| CN-103382144-A | Alkyl aromatic alpha- halogenation method | UNIV HEBEI SCIENCE & TECH | 2013-11-06 | — | — | CN | claimed |
| US-6989052-B1 | Phase change ink printing process | XEROX CORPORATION (US) | 2006-01-24 | — | — | US | claimed |
| WO-2024044778-A2 | NOVEL MODULATORS OF FSHR AND USES THEREOF | CELMATIX INC. (US) | 2024-02-29 | — | — | WO | disclosed |
| US-11912693-B2 | Compounds for modulating S1P1 activity and methods of using the same | TREVENA, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| EP-4319872-A1 | THIAZOLE/ISOTHIAZOLE HSD17B13 INHIBITORS AND USES THEREOF | Inipharm, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| US-11839679-B2 | Gamma-diketones for treatment and prevention of aging skin and wrinkles | BIOSPLICE THERAPEUTICS, INC. (US) | 2023-12-12 | — | — | US | disclosed |
| US-20230357164-A1 | NOVEL QUINAZOLINE DERIVATIVE HAVING FLT3 INHIBITORY ACTIVITY, AND USE THEREOF | INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) | 2023-11-09 | — | — | US | disclosed |
| US-11807624-B2 | Substituted pyrimidinones as agonists of the APJ receptor | AMGEN INC. (US) | 2023-11-07 | — | — | US | disclosed |
| US-20230337677-A1 | ARYL AND PYRIDYL AMIDE PESTICIDES AND COMPOSITIONS THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2023-10-26 | — | — | US | disclosed |
| US-20230331751-A1 | STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES | Atea Pharmaceuticals, Inc. (US) | 2023-10-19 | — | — | US | disclosed |
| US-5405867-A | Milbemycin derivatives with insecticidal and anthelmintic properties; for plants and animals | SANKYO COMPANY, LIMITED (JP) | 1995-04-11 | — | — | US | disclosed |
| EP-0394644-A2 | Halobenzene derivatives | BAYER AG (DE) | 1990-10-31 | — | — | EP | disclosed |
| US-4963582-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO COMPANY LIMITED (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0246739-A2 | Macrolide compounds, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1987-11-25 | — | — | EP | disclosed |
| EP-0084128-B1 | PROCESS FOR THE PREPARATION OF ALKYLBENZENES SUBSTITUTED BY RADICALS CONTAINING FLUORINE | BAYER AG (DE) | 1987-01-21 | — | — | EP | disclosed |
| EP-0084128-A1 | Process for the preparation of alkylbenzenes substituted by radicals containing fluorine | BAYER AG (DE) | 1983-07-27 | — | — | EP | disclosed |
| EP-0016132-A1 | NEW SUBSTITUTED PHENYLUREA HERBICIDE | RHONE-POULENC AGROCHIMIE (FR) | 1980-10-01 | — | — | EP | disclosed |
| WO-1980000344-A1 | NEW SUBSTITUTED PHENYLUREA HERBICIDE | RHONE POULENC AGROCHIMIE (FR) | 1980-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11912693-B2 | Compounds for modulating S1P1 activity and methods of using the same | S1PR1, S1PR2, S1PR3 | IDO1 1626/4885POLQ 4412/4885NPSR1 27/4885 |
| US-11839679-B2 | Gamma-diketones for treatment and prevention of aging skin and wrinkles | DGKG, DGKA, DNER | IDO1 810/4885POLQ 644/4885NPSR1 3879/4885 |
| US-20230331751-A1 | STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES | NUDT1, PNP, ATIC | IDO1 2945/4885POLQ 869/4885NPSR1 755/4885 |
| US-20230337677-A1 | ARYL AND PYRIDYL AMIDE PESTICIDES AND COMPOSITIONS THEREOF | DDT, ACHE, AHR | IDO1 32/4885POLQ 4179/4885NPSR1 1223/4885 |
| US-20230357164-A1 | NOVEL QUINAZOLINE DERIVATIVE HAVING FLT3 INHIBITORY ACTIVITY, AND USE THEREOF | FLT3, ABL1, MCL1 | IDO1 1596/4885POLQ 4259/4885NPSR1 2726/4885 |
| US-11807624-B2 | Substituted pyrimidinones as agonists of the APJ receptor | APLNR, AGTR1, AGTR2 | IDO1 3700/4885POLQ 2256/4885NPSR1 254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.