Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | DHFR | P00374 | 2/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9782470 | 1.00 | ALOX5 (0.36) | ALOX5MAPK14KDRDHFRP2RY12 | |
| SCHEMBL8721880 | 1.00 | ALOX5 (0.36) | ALOX5MAPK14KDRDHFRP2RY12 | |
| SCHEMBL6885924 | 0.86 | TYMS (0.37) | KDRDHFRP2RY12TDP1TYMS | |
| SCHEMBL6885928 | 0.86 | TYMS (0.37) | KDRDHFRP2RY12TDP1TYMS | |
| SCHEMBL9782611 | 0.83 | ITGA4 (0.43) | TDP1GAAMAPT | |
| SCHEMBL8722807 | 0.83 | ITGA4 (0.43) | TDP1GAAMAPT | |
| SCHEMBL6448813 | 0.82 | L3MBTL1 (0.53) | ALOX5DHFRTYMS | |
| SCHEMBL27519961 | 0.82 | L3MBTL1 (0.53) | ALOX5DHFRTYMS | |
| SCHEMBL6448822 | 0.82 | L3MBTL1 (0.53) | ALOX5DHFRTYMS | |
| SCHEMBL9724178 | 0.82 | TYMS (0.38) | KDRDHFRP2RY12TDP1TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506267-A | IMMUNOADJUVANT FOR BONE MARROW CELL GROWTH AFTERTREATMENT OF CHEMOTHERAPY OR RADIOTHERAPY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0641776-A2 | Thioglycerol derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |