Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9230466 | 0.85 | TAAR1 (0.42) | SMN1; SMN2RAB9AAOC3 | |
| SCHEMBL9230556 | 0.80 | — | — | |
| SCHEMBL8506410 | 0.79 | TAAR1 (0.40) | SMN1; SMN2RAB9AAOC3 | |
| SCHEMBL5484319 | 0.76 | ADRB2 (0.46) | ADRB2C3AR1SLC6A2SLC6A3AKT1 | |
| SCHEMBL9079639 | 0.76 | ACHE (0.39) | CYP19A1 | |
| SCHEMBL30798706 | 0.74 | ADRB2 (0.45) | ADRB2C3AR1SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL9081434 | 0.74 | AOC3 (0.44) | RAB9AAOC3 | |
| SCHEMBL9078974 | 0.73 | L3MBTL1 (0.42) | SMN1; SMN2RAB9ACYP19A1TSHRMAPK1 | |
| SCHEMBL8504349 | 0.73 | MEN1 (0.42) | C3AR1SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL8505569 | 0.73 | SLC6A2 (0.39) | ADRB2SLC6A2SLC6A3SLC6A4AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5436358-A | 2-(aryl)propylalkylpolysiloxane type silicone fluids and methods of making them | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1995-07-25 | — | — | US | disclosed |