Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5490217 | 0.89 | IDO1 (0.38) | ADRB2TP53HPGDAOC3IDO1 | |
| SCHEMBL5494536 | 0.83 | ACHE (0.44) | CYP19A1TSHRTDP1LMNAAOC3 | |
| SCHEMBL5489949 | 0.81 | AOC3 (0.35) | ADRB2AOC3IDO1TDO2 | |
| SCHEMBL5487989 | 0.81 | PYCR1 (0.37) | MAPK1CYP2A6 | |
| SCHEMBL5413664 | 0.80 | TAAR1 (0.52) | TSHRAOC3 | |
| SCHEMBL11839524 | 0.79 | ESR1 (0.38) | TSHRMAPK1TDP1AOC3IDO1 | |
| SCHEMBL5491106 | 0.79 | L3MBTL1 (0.48) | TSHRMAPK1TDP1LMNATP53 | |
| SCHEMBL5490777 | 0.78 | GRIA4 (0.46) | AOC3 | |
| SCHEMBL9230224 | 0.76 | ADRB2 (0.37) | ADRB2C3AR1CYP19A1TSHRMAPK1 | |
| SCHEMBL8505735 | 0.75 | SLC6A2 (0.42) | ADRB2C3AR1AKT1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |
| US-5527938-A | FRIEDEL-CRAFT ALKYLATION OF AROMATIC COMPOUNDS WITH ALLYLCHLOROSILANES USING LEWIS ACID CATALYST | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1996-06-18 | — | — | US | disclosed |