Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9079639 | 0.83 | ACHE (0.39) | CYP19A1 | |
| SCHEMBL9081434 | 0.81 | AOC3 (0.44) | ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL5491106 | 0.80 | L3MBTL1 (0.48) | L3MBTL1TSHRMAPK1ATMTDP1 | |
| SCHEMBL8505906 | 0.79 | CYP19A1 (0.40) | ALDH1A1CYP19A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9080321 | 0.75 | AOC3 (0.40) | ALDH1A1NPC1RAB9A | |
| SCHEMBL8506410 | 0.75 | TAAR1 (0.40) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9081242 | 0.75 | AOC3 (0.40) | ALDH1A1NPC1RAB9A | |
| SCHEMBL11348459 | 0.73 | CYP1A2 (0.37) | ESR1ESR2ALDH1A1CYP19A1HPGD | |
| SCHEMBL9230224 | 0.73 | ADRB2 (0.37) | TSHRMAPK1TDP1CYP19A1LMNA | |
| SCHEMBL9230466 | 0.71 | TAAR1 (0.42) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527934-A | HYDROSILATING BIS(DICHLOROSILYL)METHANES WITH ORGANOOLEFINS OR ORGANOSILYLOLEFINS IN THE PRESENCE OF CHLOROPLATINIC ACID CATALYST | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1996-06-18 | — | — | US | disclosed |