Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 8/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306386 | 0.87 | MAPK1 (0.47) | MAPK1L3MBTL1PTPN1ACP1CDC25B | |
| SCHEMBL7305151 | 0.82 | MAPK1 (0.39) | MAPK1L3MBTL1MAOADRD2DRD3 | |
| SCHEMBL7316915 | 0.82 | MAPK1 (0.45) | MAPK1L3MBTL1 | |
| SCHEMBL14168364 | 0.81 | MAOA (0.38) | MAPK1L3MBTL1MAOAPTPN1ACP1 | |
| SCHEMBL10151437 | 0.81 | MAOA (0.38) | MAPK1L3MBTL1MAOAPTPN1ACP1 | |
| SCHEMBL15757164 | 0.80 | MAPK1 (0.48) | MAPK1L3MBTL1GRM2DRD2DRD3 | |
| SCHEMBL7229039 | 0.79 | MAPK1 (0.36) | MAPK1L3MBTL1MAOA | |
| SCHEMBL7313654 | 0.79 | MAPK1 (0.41) | MAPK1L3MBTL1MAOA | |
| SCHEMBL7314320 | 0.79 | MAPK1 (0.37) | MAPK1L3MBTL1 | |
| SCHEMBL15219403 | 0.78 | MAPK1 (0.35) | MAPK1L3MBTL1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647634-A1 | Method of preparing a heterocyclic intermediate for the production of optically active aryloxy-substituted vicinal aminoalcohols | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1995-04-12 | — | — | EP | disclosed |
| EP-0647633-A1 | Method of preparing a heterocyclic intermediate for the production of optically active aryloxysubstituted vicinal aminoalcohols | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1995-04-12 | — | — | EP | disclosed |