SCHEMBL15219403

SCHEMBL15219403

CS(=O)(=O)OC[C@H]1CN(C/C=C/F)C(=O)O1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MAOA P21397 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9230345 0.78 MAPK1 (0.49) MAPK1L3MBTL1MAOA
SCHEMBL14168364 0.74 MAOA (0.38) MAPK1L3MBTL1MAOA
SCHEMBL10151437 0.74 MAOA (0.38) MAPK1L3MBTL1MAOA
SCHEMBL7305151 0.73 MAPK1 (0.39) MAPK1L3MBTL1MAOA
SCHEMBL7316915 0.73 MAPK1 (0.45) MAPK1L3MBTL1
SCHEMBL7307020 0.73 MAPK1 (0.35) MAPK1L3MBTL1
SCHEMBL7229039 0.72 MAPK1 (0.36) MAPK1L3MBTL1MAOA
SCHEMBL9230346 0.71 HTR2B (0.41) MAPK1L3MBTL1MAOA
SCHEMBL9230342 0.71 HTR2B (0.41) MAPK1L3MBTL1MAOA
SCHEMBL10368362 0.71 CA2 (0.47) MAPK1L3MBTL1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2388251-B1 METHOD FOR PREPARING LINEZOLID AND INTERMEDIATES THEREOF LIANHE CHEMICAL TECHNOLOGY CO LTD (CN) 2013-08-28 EP disclosed