Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306386 | 0.91 | MAPK1 (0.47) | MAPK1L3MBTL1MEN1KMT2A | |
| SCHEMBL7310863 | 0.87 | MAPK1 (0.40) | MAPK1L3MBTL1 | |
| SCHEMBL7305151 | 0.84 | MAPK1 (0.39) | MAPK1L3MBTL1 | |
| SCHEMBL7308886 | 0.84 | MAPK1 (0.49) | MAPK1L3MBTL1ALDH1A1HTR7 | |
| SCHEMBL7314450 | 0.82 | HTR7 (0.41) | MAPK1L3MBTL1HTR7 | |
| SCHEMBL7227670 | 0.82 | CHRM2 (0.41) | MAPK1L3MBTL1 | |
| SCHEMBL9230345 | 0.82 | MAPK1 (0.49) | MAPK1L3MBTL1 | |
| SCHEMBL8858104 | 0.82 | ITGB3 (0.34) | MAPK1L3MBTL1GAA | |
| SCHEMBL7310668 | 0.82 | MAPK1 (0.49) | MAPK1L3MBTL1ALDH1A1HTR7 | |
| SCHEMBL7307020 | 0.81 | MAPK1 (0.35) | MAPK1L3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |
| EP-0727425-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-08-21 | — | — | EP | disclosed |
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |