Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9232148 | 0.91 | POLB (0.49) | POLBLMNAALDH1A1MAPTNPSR1 | |
| SCHEMBL5007472 | 0.85 | ALDH1A1 (0.49) | POLBLMNAALDH1A1MAPTNPSR1 | |
| SCHEMBL1197675 | 0.84 | ALDH1A1 (0.44) | POLBLMNAALDH1A1NPSR1MEN1 | |
| SCHEMBL11542459 | 0.83 | LAP3 (0.42) | POLBLMNAALDH1A1NPSR1MEN1 | |
| SCHEMBL12876278 | 0.81 | LMNA (0.46) | POLBLMNAALDH1A1MAPTNPSR1 | |
| SCHEMBL11542170 | 0.79 | TSHR (0.37) | LMNAALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL5363358 | 0.76 | ALDH1A1 (0.46) | POLBLMNAALDH1A1MAPTMEN1 | |
| SCHEMBL12876302 | 0.75 | ALDH1A1 (0.43) | POLBLMNAALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL15693584 | 0.74 | LMNA (0.45) | POLBLMNAALDH1A1MAPTNPSR1 | |
| SCHEMBL11540558 | 0.73 | ANPEP (0.48) | ALDH1A1NPSR1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3085390-B1 | COMPOUND FOR BONE SCANNING AND USE THEREOF | TAIWAN HOPAX CHEMS MFG CO LTD (TW) | 2020-02-26 | — | — | EP | disclosed |
| US-9828398-B2 | Compound for bone scanning and use thereof | TAIWAN HOPAX CHEMS. MFG. CO., LTD. (TW) | 2017-11-28 | — | — | US | disclosed |
| US-9828398-B2 | Compound for bone scanning and use thereof | TAIWAN HOPAX CHEMS. MFG. CO., LTD. (TW) | 2017-11-28 | — | — | US | disclosed |
| US-9828398-B2 | Compound for bone scanning and use thereof | TAIWAN HOPAX CHEMS. MFG. CO., LTD. (TW) | 2017-11-28 | — | — | US | disclosed |
| EP-3085390-A1 | COMPOUND FOR BONE SCANNING AND USE THEREOF | Taiwan Hopax Chems. Mfg. Co., Ltd. (TW) | 2016-10-26 | — | — | EP | disclosed |
| US-20160304545-A1 | COMPOUND FOR BONE SCANNING AND USE THEREOF | TAIWAN HOPAX CHEMS. MFG. CO., LTD. (TW) | 2016-10-20 | — | — | US | disclosed |
| US-20160304545-A1 | COMPOUND FOR BONE SCANNING AND USE THEREOF | TAIWAN HOPAX CHEMS. MFG. CO., LTD. (TW) | 2016-10-20 | — | — | US | disclosed |
| US-20160304545-A1 | COMPOUND FOR BONE SCANNING AND USE THEREOF | TAIWAN HOPAX CHEMS. MFG. CO., LTD. (TW) | 2016-10-20 | — | — | US | disclosed |
| US-8946144-B2 | Phosphonated glycopeptide and lipoglycopeptide antibiotics and uses thereof for the prevention and treatment of bone and joint infections | THE MEDICINES COMPANY (US) | 2015-02-03 | — | — | US | disclosed |
| US-8946144-B2 | Phosphonated glycopeptide and lipoglycopeptide antibiotics and uses thereof for the prevention and treatment of bone and joint infections | THE MEDICINES COMPANY (US) | 2015-02-03 | — | — | US | disclosed |
| WO-2010019511-A2 | PHOSPHONATED RIFAMYCINS AND USES THEREOF FOR THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS | TARGANTA THERAPEUTICS CORP. (US) | 2010-02-18 | — | — | WO | disclosed |
| WO-2010019511-A2 | PHOSPHONATED RIFAMYCINS AND USES THEREOF FOR THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS | TARGANTA THERAPEUTICS CORP. (US) | 2010-02-18 | — | — | WO | disclosed |
| US-20080287396-A1 | Phosphonated Fluoroquinolones, Antibacterial Analogs Thereof, and Methods for the Prevention and Treatment of Bone and Joint Infections | TARGANTA THERAPEUTICA INC. (CA) | 2008-11-20 | — | — | US | disclosed |
| US-20080287396-A1 | Phosphonated Fluoroquinolones, Antibacterial Analogs Thereof, and Methods for the Prevention and Treatment of Bone and Joint Infections | TARGANTA THERAPEUTICA INC. (CA) | 2008-11-20 | — | — | US | disclosed |
| US-20080287396-A1 | Phosphonated Fluoroquinolones, Antibacterial Analogs Thereof, and Methods for the Prevention and Treatment of Bone and Joint Infections | TARGANTA THERAPEUTICA INC. (CA) | 2008-11-20 | — | — | US | disclosed |
| US-7420000-B2 | Amino phosphonate and amino bis-phosphonate derivatives | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2008-09-02 | — | — | US | disclosed |
| US-7420000-B2 | Amino phosphonate and amino bis-phosphonate derivatives | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2008-09-02 | — | — | US | disclosed |
| EP-0546548-B1 | Guanidinyl alkyl-1,1-bis phosphonic acid derivatives, process for their preparation and their use | HOECHST AG (DE) | 1997-05-02 | — | — | EP | disclosed |
| US-5294608-A | Compounds for treatment of osteoporosis and bone disorders | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-15 | — | — | US | disclosed |
| EP-0546548-A1 | Guanidinyl alkyl-1,1-bis phosphonic acid derivatives, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304545-A1 | COMPOUND FOR BONE SCANNING AND USE THEREOF | SOST, BPGM, PPIP5K2 | POLB 3031/4885LMNA 4552/4885ALDH1A1 4679/4885 |
| US-20080287396-A1 | Phosphonated Fluoroquinolones, Antibacterial Analogs Thereof, and Methods for the Prevention and Treatment of Bone and Joint Infections | BPGM, PSPH, PGLS | POLB 237/4885LMNA 3228/4885ALDH1A1 4175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.