Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 4/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL9229650 | 0.96 | HPGDS (0.42) | HPGDSF10ITGB3ITGA2BPRSS1 | |
| Trifluoroacetic Acid SCHEMBL8866136 | 0.88 | ITGB3 (0.49) | HPGDSF10ITGB3ITGA2BPRSS1 | |
| Trifluoroacetic Acid SCHEMBL9230148 | 0.87 | HPGDS (0.41) | HPGDSALDH1A1KDM4ENPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL8866967 | 0.85 | ITGB3 (0.51) | HPGDSF10ITGB3ITGA2BPRSS1 | |
| SCHEMBL9233193 | 0.84 | HPGDS (0.42) | HPGDSF10PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL9232906 | 0.83 | HTR2A (0.42) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL9235366 | 0.81 | SUV39H2 (0.44) | F10ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL9236237 | 0.81 | ALDH1A1 (0.41) | HPGDSALDH1A1KDM4ENPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL2128057 | 0.81 | ALDH1A3 (0.51) | HPGDSALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL9235402 | 0.81 | HPGDS (0.42) | HPGDSF10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668278-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1995-08-23 | — | — | EP | disclosed |