Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL923003 | 0.86 | CYP1A2 (0.43) | CYP1A2CYP3A4CYP2C19KCNH2KDM4E | |
| SCHEMBL925112 | 0.79 | MAPT (0.51) | CYP1A2CYP3A4CYP2C19KCNH2KDM4E | |
| SCHEMBL14749252 | 0.75 | MAPT (0.38) | KDM4EBRCA1HSD17B10SMN1; SMN2HTT | |
| SCHEMBL885485 | 0.75 | NOTUM (0.49) | CYP2C19KDM4EHSD17B10HTTMAPT | |
| SCHEMBL420546 | 0.74 | L3MBTL1 (0.43) | KDM4EHSD17B10SMN1; SMN2HTTMAPT | |
| SCHEMBL3061999 | 0.74 | MAPT (0.41) | KDM4EBRCA1HSD17B10LMNASMN1; SMN2 | |
| SCHEMBL2280370 | 0.72 | GAA (0.54) | KDM4ELMNASMN1; SMN2TSHRMAPT | |
| SCHEMBL13485763 | 0.71 | KDM4E (0.42) | KDM4EBRCA1HSD17B10LMNASMN1; SMN2 | |
| SCHEMBL2308270 | 0.71 | ALDH1A1 (0.39) | KDM4EBRCA1HSD17B10SMN1; SMN2HTT | |
| SCHEMBL2305192 | 0.71 | MAPT (0.42) | KDM4EBRCA1HSD17B10LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1965753-B1 | REVERSIBLY CHANGEABLE HAIR COLOR | HENKEL AG & CO KGAA (DE) | 2013-09-04 | — | — | EP | claimed |
| EP-1778176-B1 | COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2012-07-25 | — | — | EP | claimed |
| US-20100037909-A1 | SUBSTANCES FOR DYEING KERATINOUS FIBERS | HENKEL AG & CO. KGAA (DE) | 2010-02-18 | — | — | US | claimed |
| US-20080301885-A1 | REVERSIBLY CHANGEABLE HAIR COLOR | HENKEL AG & CO. KGAA (DE) | 2008-12-11 | — | — | US | claimed |
| EP-1965753-A1 | REVERSIBLY CHANGEABLE HAIR COLOR | Henkel AG & Co. KGaA (DE) | 2008-09-10 | — | — | EP | claimed |
| WO-2007073922-A1 | REVERSIBLY CHANGEABLE HAIR COLOR | HENKEL AG & CO. KGAA (DE) | 2007-07-05 | — | — | WO | claimed |
| EP-1778176-A2 | MEANS FOR COLOURING KERATIN-CONTAINING FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-05-02 | — | — | EP | claimed |
| WO-2005120445-A2 | MEANS FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-12-22 | — | — | WO | claimed |
| EP-1900393-B1 | Hydrogen peroxide activation with diones and imidazoles | HENKEL AG & CO KGAA (DE) | 2018-02-28 | — | — | EP | disclosed |
| EP-2026754-B1 | LIGHTENING AND/OR COLOURING AGENT COMPRISING CYCLIC UREA DERIVATIVES | HENKEL AG & CO KGAA (DE) | 2015-09-30 | — | — | EP | disclosed |
| CN-103370312-B | 1,3-diox-5-ketone compound | MERCK PATENT GMBH (DE) | 2015-09-30 | — | — | CN | disclosed |
| EP-2673267-B1 | 1,3-DIOXAN-5-ONE COMPOUNDS | MERCK PATENT GMBH (DE) | 2015-06-03 | — | — | EP | disclosed |
| EP-1944010-B1 | Brightening and/or colouring agent with acrylic acid derivative(s) | HENKEL AG & CO KGAA (DE) | 2015-03-11 | — | — | EP | disclosed |
| US-8907110-B2 | Benzodioxepin-3-one compounds as dyes or as fluorescent emitters | MERCK PATENT GMBH (DE) | 2014-12-09 | — | — | US | disclosed |
| WO-2006119821-A1 | AGENT FOR DYEING KERATIN-BASED FIBRES | HENKEL KOMMANDITGESELLCHAFT AUF AKTIEN (DE) | 2006-11-16 | — | — | WO | disclosed |
| WO-2006119819-A1 | AGENT FOR DYEING KERATIN-BASED FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-11-16 | — | — | WO | disclosed |
| WO-2005120445-A2 | MEANS FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-12-22 | — | — | WO | disclosed |
| US-20050272709-A1 | Immugenic compositions and diagnostic and therapeutic uses thereof | DERMIRA (CANADA), INC. | 2005-12-08 | — | — | US | disclosed |
| EP-1450791-A1 | HYDRAZONOPYRAZOLE DERIVATIVES AND THEIR USE AS THERAPEUTICS | Kinetek Pharmaceuticals, Inc. (CA) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003045379-A1 | HYDRAZONOPYRAZOLE DERIVATIVES AND THEIR USE AS THERAPEUTICS | KINETEK PHARMACEUTICALS, INC. (CA) | 2003-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272709-A1 | Immugenic compositions and diagnostic and therapeutic uses thereof | MKI67, CDK4, CCNC | CYP1A2 4210/4885CYP3A4 4371/4885CYP2C19 3704/4885 |
| US-20100037909-A1 | SUBSTANCES FOR DYEING KERATINOUS FIBERS | KRT18, H1-10, COL1A1 | CYP1A2 297/4885CYP3A4 296/4885CYP2C19 540/4885 |
| US-20080301885-A1 | REVERSIBLY CHANGEABLE HAIR COLOR | TYR, CBR3, COXFA4L2 | CYP1A2 760/4885CYP3A4 759/4885CYP2C19 943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.