Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 5/20 | 0.47 |
| ▸ | YAP1 | P46937 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 7/20 | 0.45 |
| ▸ | MMP1 | P03956 | 3/20 | 0.45 |
| ▸ | MMP3 | P08254 | 3/20 | 0.45 |
| ▸ | MMP7 | P09237 | 3/20 | 0.45 |
| ▸ | MMP9 | P14780 | 3/20 | 0.45 |
| ▸ | MMP8 | P22894 | 3/20 | 0.45 |
| ▸ | MMP2 | P08253 | 3/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | MAX | P61244 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7753284 | 0.94 | MMP13 (0.47) | TGFBR1GPR119KDM4EPKMLIMK2 | |
| SCHEMBL7753201 | 0.89 | MMP13 (0.46) | TGFBR1GPR119KDM4EPKMLIMK2 | |
| SCHEMBL8175348 | 0.88 | YAP1 (0.46) | TGFBR1YAP1GPR119KDM4EPKM | |
| SCHEMBL6977329 | 0.84 | TGFBR1 (0.43) | TGFBR1GPR119KDM4EPKMLIMK2 | |
| SCHEMBL6977326 | 0.84 | TGFBR1 (0.43) | TGFBR1GPR119KDM4EPKMLIMK2 | |
| SCHEMBL7753390 | 0.83 | YAP1 (0.55) | YAP1GPR119KDM4EPKMITGB3 | |
| SCHEMBL27449831 | 0.83 | TGFBR1 (0.51) | TGFBR1GPR119KDM4EPKMLIMK2 | |
| SCHEMBL7752618 | 0.82 | ITGB3 (0.43) | YAP1GPR119MYCMAXITGB3 | |
| SCHEMBL7752625 | 0.82 | GPR119 (0.41) | YAP1GPR119KDM4EPKMMMP13 | |
| SCHEMBL7752668 | 0.82 | KDM4E (0.51) | TGFBR1GPR119KDM4EPKMLIMK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725059-B1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMA (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-6048854-A | ANTICOAGULANTS; ANTICANCER AGENT; WOUND HEALING AGENTS;BONE DISORDERS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| US-5707994-A | USEFUL AS A PLATELET AGGREGATION INHIBITOR, CANCER METASTASIS INHIBITOR, WOUND HEALING AGENT OR A BONE RESORPTION INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0725059-A1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-08-07 | — | — | EP | disclosed |