Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7131959 | 0.88 | BRD4 (0.36) | ALDH1A1SMN1; SMN2LMNATDP1HSD17B10 | |
| SCHEMBL5972535 | 0.85 | MEN1 (0.36) | ALDH1A1SMN1; SMN2LMNATDP1HSD17B10 | |
| SCHEMBL27279407 | 0.84 | MEN1 (0.35) | ALDH1A1SMN1; SMN2LMNATDP1HSD17B10 | |
| SCHEMBL7042697 | 0.82 | KDM4C (0.35) | ALDH1A1LMNATDP1KDM4CCYP11B1 | |
| SCHEMBL28768435 | 0.80 | MAPT (0.39) | ALDH1A1LMNATDP1HSD17B10MAPT | |
| SCHEMBL633608 | 0.80 | BRD4 (0.34) | ALDH1A1SMN1; SMN2LMNATDP1HSD17B10 | |
| SCHEMBL13727682 | 0.79 | KDM4E (0.44) | ALDH1A1SMN1; SMN2TDP1GRM5HSD17B10 | |
| SCHEMBL8418862 | 0.79 | LMNA (0.36) | ALDH1A1SMN1; SMN2LMNATDP1HSD17B10 | |
| SCHEMBL4220132 | 0.78 | MAOA (0.40) | ALDH1A1SMN1; SMN2LMNATDP1CYP2C19 | |
| SCHEMBL28567301 | 0.78 | CAMKK2 (0.42) | SMN1; SMN2LMNACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0484027-B1 | Polysubstituted phthalocyanines | ZENECA LTD (GB) | 1996-12-18 | — | — | EP | disclosed |