SCHEMBL9235448

SCHEMBL9235448

CCCC1=CCCc2ccccc21

nearest known ligand 0.66

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 5/20 0.50
MPO P05164 1/20 0.42
CES1 P23141 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5614129 0.88 SIGMAR1 (0.53) SIGMAR1MPO
SCHEMBL11503302 0.85 MPO (0.57) SIGMAR1MPOCES1
SCHEMBL7406702 0.81 SIGMAR1 (0.50) SIGMAR1MPOCES1
SCHEMBL5859128 0.81 HTR6 (0.50) SIGMAR1
SCHEMBL27294942 0.80 SIGMAR1 (0.59) SIGMAR1
Hydrochloric Acid SCHEMBL8894987 0.80 SIGMAR1 (0.49) SIGMAR1MPOCES1
SCHEMBL14290594 0.79 SIGMAR1 (0.55) SIGMAR1
SCHEMBL11543020 0.78 SIGMAR1 (0.51) SIGMAR1
SCHEMBL28294223 0.78 SIGMAR1 (0.45) SIGMAR1
SCHEMBL2952166 0.78 SIGMAR1 (0.71) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107085033-B Application of the N- phenylnaphthalene aminated compounds as MALDI matrix 中国科学院化学研究所 2019-07-19 CN disclosed
EP-0686637-A1 Tetracyclic 1,4-oxazine derivatives, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1995-12-13 EP disclosed