Sugi Predict

Sugi Predict / Compounds / SCHEMBL9237396

SCHEMBL9237396

SCHEMBL9237396

CN(C)S(=O)(=O)n1ccc2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ HTR6 P50406 6/20 0.56
▸ HTT P42858 4/20 0.56
▸ MEN1 O00255 2/20 0.56
▸ KMT2A Q03164 2/20 0.56
▸ TSHR P16473 2/20 0.56
▸ LMNA P02545 2/20 0.56
▸ ALDH1A1 P00352 1/20 0.56
▸ HPGD P15428 1/20 0.56
▸ MAPT P10636 1/20 0.51
▸ NPSR1 Q6W5P4 1/20 0.51
▸ RAPGEF4 Q8WZA2 1/20 0.51
▸ TDP1 Q9NUW8 1/20 0.51
▸ PKM P14618 1/20 0.50
▸ L3MBTL1 Q9Y468 1/20 0.50
▸ SMN1; SMN2 Q16637 2/20 0.46
▸ HTR2A P28223 1/20 0.42
▸ HTR2C P28335 1/20 0.42
▸ NOTUM Q6P988 1/20 0.42
▸ SLC6A2 P23975 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29723138 1.00 HTR6 (0.56) HTR6HTTMEN1KMT2ATSHR
SCHEMBL10433225 0.79 HTR6 (0.58) HTR6HTTMEN1KMT2ATSHR
SCHEMBL29558089 0.79 HTR6 (0.61) HTR6HTTMEN1KMT2ATSHR
SCHEMBL4065276 0.79 HTR6 (0.61) HTR6HTTMEN1KMT2ATSHR
SCHEMBL8415487 0.78 HTR6 (0.66) HTR6HTTMEN1KMT2ATSHR
SCHEMBL9737263 0.76 RAPGEF4 (0.56) HTR6HTTTSHRRAPGEF4SMN1; SMN2
SCHEMBL29723148 0.76 FABP4 (0.50) HTR6HTTMEN1KMT2ALMNA
SCHEMBL6359369 0.76 HTR6 (0.58) HTR6HTTMEN1KMT2ATSHR
SCHEMBL24596834 0.75 HTR6 (0.61) HTR6HTTMEN1KMT2ATSHR
SCHEMBL5636978 0.75 HTR6 (0.61) HTR6HTTMEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102791688-A Estrogen receptor ligands KAROBIO AB 2012-11-21 — — CN claimed
CN-117402143-A EGFR inhibitor and preparation and application thereof 上海翰森生物医药科技有限公司 2024-01-16 — — CN disclosed
CN-117069700-A EGFR inhibitor and preparation and application thereof 上海翰森生物医药科技有限公司 2023-11-17 — — CN disclosed
CN-117050062-A EGFR inhibitor and preparation and application thereof 上海翰森生物医药科技有限公司 2023-11-14 — — CN disclosed
CN-114621215-B Benzothiadiazole fluorescent dye containing N, N-dimethyl sulfonamide structure and application thereof 三峡大学 2023-10-27 — — CN disclosed
CN-111187221-B EGFR inhibitor and preparation and application thereof 上海翰森生物医药科技有限公司 2023-09-26 — — CN disclosed
CN-111171000-B EGFR inhibitor and preparation and application thereof 上海翰森生物医药科技有限公司 2023-09-01 — — CN disclosed
CN-111170999-B EGFR inhibitor and preparation and application thereof 上海翰森生物医药科技有限公司 2023-06-30 — — CN disclosed
CN-114621215-A Benzothiadiazole fluorescent dye containing N, N-dimethyl sulfonamide structure and application thereof 三峡大学 2022-06-14 — — CN disclosed
CN-111187221-A EGFR inhibitor and preparation and application thereof 上海翰森生物医药科技有限公司 2020-05-22 — — CN disclosed
CN-111171000-A EGFR inhibitor and preparation and application thereof 上海翰森生物医药科技有限公司 2020-05-19 — — CN disclosed
CN-111170999-A EGFR inhibitor and preparation and application thereof 上海翰森生物医药科技有限公司 2020-05-19 — — CN disclosed
CN-102791688-B Estrogen receptor ligands KAROBIO AB 2014-11-12 — — CN disclosed
CN-102791688-A Estrogen receptor ligands KAROBIO AB 2012-11-21 — — CN disclosed
EP-0683430-A2 Photographic processing compositions including hydrophobically modified thickening agent POLAROID CORPORATION (US) 1995-11-22 — — EP disclosed