Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 2/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 11/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.37 |
| ▸ | RELA | Q04206 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9238392 | 0.82 | GGT1 (0.47) | — | |
| SCHEMBL9233436 | 0.81 | ANPEP (0.40) | PSMB5 | |
| SCHEMBL9238002 | 0.80 | ALDH1A1 (0.40) | — | |
| SCHEMBL9234753 | 0.76 | P2RX7 (0.43) | — | |
| SCHEMBL9239495 | 0.75 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL9238649 | 0.73 | ALDH1A1 (0.43) | L3MBTL1 | |
| SCHEMBL1667210 | 0.72 | GGT1 (0.42) | — | |
| SCHEMBL1667207 | 0.72 | GGT1 (0.42) | — | |
| SCHEMBL7622435 | 0.71 | CTSC (0.42) | — | |
| SCHEMBL3217867 | 0.71 | CTSC (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675112-A1 | Imidazole-containing inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-10-04 | — | — | EP | claimed |
| EP-0675112-A1 | Imidazole-containing inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-10-04 | — | — | EP | disclosed |