Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ACE | P12821 | 8/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9238392 | 0.87 | GGT1 (0.47) | ACECTSSCTSKCTSL | |
| SCHEMBL15387340 | 0.81 | ALDH1A1 (0.34) | SMN1; SMN2KMT2AKDM4EHPGDHSD17B10 | |
| SCHEMBL9239503 | 0.78 | CYP3A4 (0.40) | SMN1; SMN2CYP3A4MAPTELANEMMP8 | |
| SCHEMBL1667207 | 0.76 | GGT1 (0.42) | SMN1; SMN2ACEMEN1KMT2ACYP3A4 | |
| SCHEMBL1667210 | 0.76 | GGT1 (0.42) | SMN1; SMN2ACEMEN1KMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL11206033 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2ACEABCB11LMNACYP3A4 | |
| SCHEMBL3337996 | 0.76 | CTSK (0.39) | MEN1KMT2AMAPTCTSK | |
| SCHEMBL10482405 | 0.75 | SMN1; SMN2 (0.55) | SMN1; SMN2ACEABCB11LMNAMEN1 | |
| SCHEMBL14265369 | 0.75 | SMN1; SMN2 (0.55) | SMN1; SMN2ACEABCB11LMNAMEN1 | |
| SCHEMBL9237438 | 0.75 | MASP2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675112-A1 | Imidazole-containing inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-10-04 | — | — | EP | disclosed |