Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22983976 | 0.88 | ADORA3 (0.40) | ADORA2AADORA2BADORA3 | |
| SCHEMBL29674405 | 0.88 | ADORA3 (0.40) | ADORA2AADORA2BADORA3 | |
| SCHEMBL9565119 | 0.86 | ADORA3 (0.38) | ADORA2AADORA2BADORA3 | |
| SCHEMBL12729571 | 0.79 | ADORA3 (0.33) | ADORA2AADORA2BADORA3 | |
| SCHEMBL6893059 | 0.77 | ADORA3 (0.39) | ADORA3ADORA1 | |
| SCHEMBL8922716 | 0.77 | PRMT6 (0.36) | ADORA2AADORA2B | |
| SCHEMBL17772331 | 0.77 | STING1 (0.52) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL8624094 | 0.77 | STING1 (0.52) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL12729578 | 0.77 | STING1 (0.52) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL12222444 | 0.77 | STING1 (0.52) | ADORA2AADORA2BADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649855-A1 | Use of nucleosides and nucleoside derivatives with enzymatically cleavable protecting groupes in the synthesis of oligonucleotiden | Roche Diagnostics GmbH (DE) | 1995-04-26 | — | — | EP | disclosed |