Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29674405 | 1.00 | ADORA3 (0.40) | ADORA3PRMT6ADORA2AADORA2B | |
| SCHEMBL6893059 | 0.88 | ADORA3 (0.39) | ADORA3 | |
| SCHEMBL9237960 | 0.88 | ADORA2A (0.42) | ADORA3ADORA2AADORA2B | |
| SCHEMBL9565119 | 0.88 | ADORA3 (0.38) | ADORA3ADORA2AADORA2B | |
| SCHEMBL8922716 | 0.86 | PRMT6 (0.36) | PRMT6ADORA2AADORA2B | |
| SCHEMBL10239015 | 0.86 | PRMT6 (0.38) | PRMT6ADORA2AADORA2B | |
| SCHEMBL22984018 | 0.85 | PDE4A (0.47) | ADORA2AADORA2B | |
| SCHEMBL19509705 | 0.85 | PDE4A (0.47) | ADORA2AADORA2B | |
| SCHEMBL22577522 | 0.85 | ADK (0.34) | — | |
| SCHEMBL10459187 | 0.85 | PDE4A (0.47) | ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159922-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230159922-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| EP-4013428-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | Ionis Pharmaceuticals, Inc. (US) | 2022-06-22 | — | — | EP | disclosed |
| WO-2021030763-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2021-02-18 | — | — | WO | disclosed |