Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 8/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29674405 | 0.88 | ADORA3 (0.40) | ADORA3 | |
| SCHEMBL22983976 | 0.88 | ADORA3 (0.40) | ADORA3 | |
| SCHEMBL6899409 | 0.80 | PDE4D (0.49) | ADORA3ADORA1NT5E | |
| SCHEMBL22983967 | 0.79 | ABL1 (0.37) | ADORA3ADORA1NT5E | |
| SCHEMBL9237960 | 0.77 | ADORA2A (0.42) | ADORA3ADORA1 | |
| SCHEMBL9565119 | 0.77 | ADORA3 (0.38) | ADORA3 | |
| SCHEMBL22577522 | 0.77 | ADK (0.34) | — | |
| SCHEMBL7921755 | 0.77 | ACHE (0.37) | — | |
| SCHEMBL8922716 | 0.77 | PRMT6 (0.36) | — | |
| SCHEMBL8668421 | 0.76 | NT5E (0.36) | NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604409-B1 | OLIGONUCLEOTIDE ANALOGS FOR DETECTING AND MODULATING RNA ACTIVITY AND GENE EXPRESSION | ISIS PHARMACEUTICALS INC (US) | 2004-07-14 | — | — | EP | disclosed |
| EP-1418179-A2 | Compositions and methods for detecting and modulating rna activity and gene expression | ISIS PHARMACEUTICALS, INC. (US) | 2004-05-12 | — | — | EP | disclosed |
| US-6262241-B1 | ANTISENSE COMPOUNDS WHICH CLEAVE PHOSPHORODIESTER BONDS AND IMPROVE PHARMACODYNAMIC AND PHARMACOKINETIC PROPERTIES OF OLIGONUCLEOTIDES, USEFUL IN DIAGNOSING DISEASES | ISIS PHARMACEUTICALS, INC. | 2001-07-17 | — | — | US | disclosed |