Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9241871 | 0.87 | EGFR (0.43) | ALDH1A1KDM4EKCNH2HCRTR1KMT2A | |
| SCHEMBL9238106 | 0.83 | LMNA (0.41) | ALDH1A1KDM4EHPGDHSD17B10PTGDR2 | |
| SCHEMBL19547602 | 0.78 | ENPP2 (0.45) | ALDH1A1KDM4EHPGDHSD17B10PTGDR2 | |
| SCHEMBL8687378 | 0.78 | KDM4E (0.49) | ALDH1A1KDM4EHPGDHSD17B10SRC | |
| SCHEMBL7076535 | 0.74 | CCR2 (0.56) | KDM4EHPGDHSD17B10 | |
| SCHEMBL9240535 | 0.74 | EGFR (0.42) | ALDH1A1KDM4EHPGDHSD17B10HCRTR1 | |
| SCHEMBL9236400 | 0.72 | ACLY (0.47) | ALDH1A1KDM4EHPGDHCRTR1KMT2A | |
| SCHEMBL8689246 | 0.71 | MAPT (0.48) | ALDH1A1KDM4EHPGDHSD17B10AKR1C3 | |
| SCHEMBL9241874 | 0.69 | LMNA (0.50) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL9243614 | 0.69 | KDM4E (0.60) | ALDH1A1KDM4EHPGDHSD17B10SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639573-A1 | Benzocondensed five membered heterocycles, process of their preparation, their use as drug, as diagnostic means and pharmaceuticals containing it | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-02-22 | — | — | EP | disclosed |