Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.53 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 4/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9232927 | 0.89 | NAAA (0.68) | NAAALMNAPAX8KDM4A | |
| SCHEMBL1173971 | 0.86 | PKM (0.57) | NAAACES2CES1LMNAPOLB | |
| SCHEMBL11402447 | 0.84 | CYP3A4 (0.53) | NAAACES2CES1POLBCNR1 | |
| SCHEMBL17596634 | 0.84 | CES2 (0.52) | NAAACES2CES1POLBCNR1 | |
| SCHEMBL4207067 | 0.83 | LAP3 (0.55) | CES2CES1LMNAPOLBCNR1 | |
| SCHEMBL17596567 | 0.83 | CES2 (0.50) | NAAACES2CES1POLBCNR1 | |
| SCHEMBL6432979 | 0.82 | CNR1 (0.69) | CNR1CNR2 | |
| SCHEMBL28658959 | 0.81 | GPR88 (0.56) | NAAALMNAPAX8POLBCNR1 | |
| SCHEMBL19205721 | 0.81 | NAAA (0.77) | NAAALMNAPAX8POLBCNR1 | |
| SCHEMBL19245448 | 0.81 | GPR88 (0.56) | NAAALMNAPAX8POLBCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657452-A1 | Imidazopyridines | MERCK PATENT GmbH (DE) | 1995-06-14 | — | — | EP | disclosed |