Urea

Urea

SCHEMBL9239354

NC(N)=O.O=[N+]([O-])[O-].O=[N+]([O-])[O-].O=[N+]([O-])[O-].[Al+3]

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.50
ALDH1A1 P00352 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
OR51E2 Q9H255 1/20 0.50
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
CA5A P35218 1/20 0.43
CA5B Q9Y2D0 1/20 0.43
TSHR P16473 2/20 0.36
CYP3A4 P08684 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ACHE P22303 1/20 0.36
BLM P54132 3/20 0.35
LDHA P00338 2/20 0.35
ALOX15 P16050 1/20 0.33
PMP22 Q01453 1/20 0.33
GAA P10253 1/20 0.32
HBB P68871 1/20 0.32
HIF1A Q16665 1/20 0.32
LDHB P07195 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL28860899 0.92 LMNA (0.50) LMNAALDH1A1TDP1OR51E2MEN1
Urea SCHEMBL30614197 0.92 LMNA (0.50) LMNAALDH1A1TDP1OR51E2MEN1
Urea SCHEMBL28695468 0.92 LMNA (0.50) LMNAALDH1A1TDP1OR51E2MEN1
Urea SCHEMBL5804636 0.92
Urea SCHEMBL21246922 0.92 LMNA (0.50) LMNAALDH1A1TDP1OR51E2MEN1
Urea SCHEMBL9575581 0.92 LMNA (0.50) LMNAALDH1A1TDP1OR51E2MEN1
Urea SCHEMBL15517775 0.92 LMNA (0.50) LMNAALDH1A1TDP1OR51E2MEN1
Urea SCHEMBL8523142 0.92
Urea SCHEMBL10483809 0.92 LMNA (0.50) LMNAALDH1A1TDP1OR51E2MEN1
Urea SCHEMBL27486703 0.92 LMNA (0.50) LMNAALDH1A1TDP1OR51E2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3898913-B1 PROCESS FOR PRODUCING METAL ORGANIC FRAMEWORKS HENKEL AG & CO KGAA (DE) 2023-07-05 EP disclosed
US-20210309937-A1 Process For Producing Metal Organic Frameworks HENKEL AG & CO. KGAA (DE) 2021-10-07 US disclosed
CN-103318931-B The method of boehmite pattern is regulated and controled in a kind of microwave attenuation materials process TAISHAN HOSPITAL (CN) 2015-07-29 CN disclosed
CN-103318931-A Method for regulating boehmite morphology in microwave hydrothermal synthesis process UNIVTAISHAN MEDICAL 2013-09-25 CN disclosed
WO-1995018081-A1 UREA-CONTAINING FERTILIZER NORSK HYDRO A.S (NO) 1995-07-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210309937-A1 Process For Producing Metal Organic Frameworks TRIM24, PUF60, TRIM28 LMNA 2290/4885ALDH1A1 452/4885TDP1 2477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.