Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9238203 | 0.85 | MTNR1A (0.37) | LTA4HMTNR1AMTNR1BPPARGPPARA | |
| SCHEMBL7661580 | 0.82 | LTA4H (0.39) | L3MBTL1LTA4HMTNR1AMTNR1BTDP1 | |
| SCHEMBL28141131 | 0.81 | LTA4H (0.37) | L3MBTL1LTA4HMTNR1AMTNR1BTDP1 | |
| SCHEMBL947518 | 0.79 | CA4 (0.41) | L3MBTL1LTA4HMTNR1AMTNR1BTDP1 | |
| SCHEMBL9715374 | 0.76 | PPARA (0.45) | L3MBTL1MTNR1AMTNR1BTDP1LMNA | |
| SCHEMBL2478675 | 0.75 | LTA4H (0.41) | L3MBTL1LTA4HMTNR1AMTNR1BTDP1 | |
| SCHEMBL4865190 | 0.74 | THRB (0.43) | L3MBTL1LTA4HMTNR1AMTNR1BTDP1 | |
| SCHEMBL945944 | 0.73 | CHRM1 (0.41) | L3MBTL1LTA4HMTNR1AMTNR1BTDP1 | |
| SCHEMBL997422 | 0.72 | LMNA (0.46) | L3MBTL1LTA4HMTNR1AMTNR1BTDP1 | |
| SCHEMBL1682635 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675895-A1 | ETOPOSIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AS A DRUG AND IN THE PREPARATION OF A DRUG FOR TREATING CANCER. | FABRE PIERRE COSMETIQUE (FR) | 1995-10-11 | — | — | EP | claimed |
| WO-1994014829-A1 | ETOPOSIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AS A DRUG AND IN THE PREPARATION OF A DRUG FOR TREATING CANCER | PIERRE FABRE MEDICAMENT (FR) | 1994-07-07 | — | — | WO | claimed |