Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.48 |
| ▸ | CFD | P00746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10680144 | 0.87 | ALOX15 (0.62) | ALOX15CFDCYP4F2CYP4A11PTGS1 | |
| SCHEMBL27316147 | 0.84 | ALOX15 (0.53) | ALOX15CFDCYP4F2CYP4A11PTGS1 | |
| SCHEMBL7111370 | 0.83 | CFD (0.43) | ALOX15CFDL3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL22064390 | 0.83 | LDHA (0.58) | ALOX15PTGS1LDHA | |
| SCHEMBL13929122 | 0.81 | AKT1 (0.56) | CFDL3MBTL1CYP4F2CYP4A11PTGS1 | |
| SCHEMBL27627503 | 0.80 | AKT1 (0.46) | ALOX15CFDCYP4F2CYP4A11PTGS1 | |
| SCHEMBL24202271 | 0.80 | CFD (0.49) | CFDL3MBTL1CYP4F2CYP4A11PTGS1 | |
| SCHEMBL22492187 | 0.80 | CFD (0.53) | CFDL3MBTL1CYP4F2CYP4A11PTGS1 | |
| SCHEMBL24201934 | 0.80 | CFD (0.49) | CFDL3MBTL1CYP4F2CYP4A11PTGS1 | |
| SCHEMBL28193150 | 0.80 | CFD (0.49) | CFDL3MBTL1CYP4F2CYP4A11PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7304688-A | — | — | None | — | — | JP | disclosed |
| CN-100562511-C | 2-aryl-acetic acids, their derivative and contain their pharmaceutical composition | DOMPE SPA (IT) | 2009-11-25 | — | — | CN | disclosed |
| CN-1768026-A | 2-aryl-acetic acids, their derivatives and pharmaceutical compositions containing them | DOMPE SPA (IT) | 2006-05-03 | — | — | CN | disclosed |
| JP-H07304688-A | NON-STEROIDAL ANTI-INFLAMMATORY DRUG, PRODUCTION THEREOF AND MEDICINE CONTAINING THE SAME | SCOTIA HOLDINGS PLC | 1995-11-21 | — | — | JP | disclosed |