Sugi Predict

Sugi Predict / Compounds / Morpholine

Morpholine

Morpholine

SCHEMBL9244682

C1COCCN1.NSc1nc2c(S)cccc2s1

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ KDM4E B2RXH2 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ PKM P14618 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2046979 0.85 PSMD14 (0.36) SMN1; SMN2KDM4EALDH1A1PKMHPGD
SCHEMBL29539652 0.85 PSMD14 (0.36) SMN1; SMN2KDM4EALDH1A1PKMHPGD
Morpholine SCHEMBL6451061 0.79 HSD17B10 (0.55) SMN1; SMN2KDM4EALDH1A1PKMHPGD
SCHEMBL83283 0.72 ALDH1A1 (0.50) SMN1; SMN2KDM4EALDH1A1HPGDALOX15
SCHEMBL1563617 0.72 PSMD14 (0.38) SMN1; SMN2KDM4EALDH1A1PKMHPGD
SCHEMBL3884834 0.72 DRD2 (0.38) —
SCHEMBL1706586 0.71 SMN1; SMN2 (0.48) SMN1; SMN2KDM4EALDH1A1PKMHPGD
SCHEMBL83284 0.71 PSMD14 (0.37) SMN1; SMN2KDM4EALDH1A1PKMHPGD
SCHEMBL7754418 0.70 ALDH1A1 (0.37) SMN1; SMN2KDM4EALDH1A1PKMHPGD
SCHEMBL8088211 0.69 ALDH1A1 (0.53) SMN1; SMN2KDM4EALDH1A1PKMHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0489313-B1 Rubber vulcanisates with good mechanical properties and with improved hysteresis behaviour BAYER AG (DE) 1995-08-09 — — EP disclosed