SCHEMBL5140991

SCHEMBL5140991

CC(CC(C)(CC(C)(C)c1ccc(O)cc1)c1ccc(O)cc1)c1ccc(O)cc1.Oc1ccc(-c2cc(-c3ccc(O)cc3)cc(-c3ccc(O)cc3)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.45
ESR1 P03372 9/20 0.38
ESR2 Q92731 7/20 0.37
KIF11 P52732 1/20 0.33
MIF P14174 1/20 0.33
PSEN1 P49768 1/20 0.33
PSEN2 P49810 1/20 0.33
APH1B Q8WW43 1/20 0.33
NCSTN Q92542 1/20 0.33
APH1A Q96BI3 1/20 0.33
PSENEN Q9NZ42 1/20 0.33
ABL1 P00519 2/20 0.33
ABCB1 P08183 2/20 0.33
BCR P11274 2/20 0.33
CYP3A4 P08684 2/20 0.33
LMNA P02545 1/20 0.33
TYR P14679 1/20 0.33
AR P10275 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18139 0.92 SHBG (0.53) SHBGESR1ESR2MIFCYP3A4
SCHEMBL6157069 0.89 SHBG (0.50) SHBGESR1ESR2MIFCYP3A4
SCHEMBL8625811 0.81 ESR1 (0.34) SHBGESR1ESR2MIFCYP3A4
SCHEMBL29113544 0.80 SHBG (0.41) SHBGESR1ESR2MIFCYP3A4
SCHEMBL2143217 0.78 ESR1 (0.47) SHBGESR1ESR2KIF11ABL1
SCHEMBL8625814 0.78 SHBG (0.39) SHBGESR1ESR2CYP3A4APP
SCHEMBL3480352 0.77 SHBG (0.52) SHBGESR1ESR2MIFCYP3A4
SCHEMBL6280436 0.77 SHBG (0.38) SHBGESR1ESR2
SCHEMBL9244771 0.76 SHBG (0.51) SHBGESR1ESR2CYP3A4LMNA
SCHEMBL9250608 0.75 ESR1 (0.37) SHBGESR1ESR2MIFCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10053537-B2 High-fluidity polycarbonate copolymer, process for production highly polymerized aromatic polycarbonate resin and aromatic polycarbonate compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2018-08-21 US disclosed
US-20170174833-A1 HIGH-FLUIDITY POLYCARBONATE COPOLYMER, PROCESS FOR PRODUCTION HIGHLY POLYMERIZED AROMATIC POLYCARBONATE RESIN AND AROMATIC POLYCARBONATE COMPOUND MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2017-06-22 US disclosed
US-20160264726-A1 HIGH-FLUIDITY POLYCARBONATE COPOLYMER, PROCESS FOR PRODUCTION HIGHLY POLYMERIZED AROMATIC POLYCARBONATE RESIN AND AROMATIC POLYCARBONATE COMPOUND MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-09-15 US disclosed
US-9353216-B2 High-fluidity polycarbonate copolymer, process for production highly polymerized aromatic polycarbonate resin and aromatic polycarbonate compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-05-31 US disclosed
US-20140206826-A1 HIGH-FLUIDITY POLYCARBONATE COPOLYMER, PROCESS FOR PRODUCTION HIGHLY POLYMERIZED AROMATIC POLYCARBONATE RESIN AND AROMATIC POLYCARBONATE COMPOUND (AS AMENDED) MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-07-24 US disclosed
EP-1381645-B1 FLAME RETARDANT RESIN COMPOSITION AND MOLDED PRODUCTS THEREOF GEN ELECTRIC (US) 2008-05-28 EP disclosed
US-20070179225-A1 Flame Retardant Resin Composition and Molded Products Thereof GENERAL ELECTRIC COMPANY (US) 2007-08-02 US disclosed
US-7112645-B2 polycarbonate that has low levels of ionic species, unreacted monomers and small molecule side products which can be detrimental to the taste and other organoleptic properties of food and beverages residing in containers made of polycarbonate GENERAL ELECTRIC COMPANY (US) 2006-09-26 US disclosed
EP-1404739-B1 OPTICAL POLYCARBONATE AND APPLICATIONS THEREOF GEN ELECTRIC (US) 2004-12-29 EP disclosed
US-6790927-B2 EXCELLENT COLOR STABILITY AND MOLDABILITY, PARTICULARLY WELL SUITED TO USE IN OPTICAL DISK SUBSTRATES GENERAL ELECTRIC COMPANY 2004-09-14 US disclosed
US-5324809-A Melt catalytic preparation of copolymeric polycarbonate from hydroquinone GE PLASTICS JAPAN, LTD. (JP) 1994-06-28 US disclosed
US-5317083-A Process for isolating polycarbonates from their solutions with tube having cross sectional contrictions BAYER AKTIENGESELLSCHAFT (DE) 1994-05-31 US disclosed
US-5306801-A Heat resistance, hue stability, water resistance GE PLASTICS JAPAN, LTD. (JP) 1994-04-26 US disclosed
US-5276109-A Molding materials with transparency GENERAL ELECTRIC COMPANY (US) 1994-01-04 US disclosed
EP-0561638-A1 Optical-grade polycarbonate resin compositions GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0561629-A2 Polycarbonate resin compositions GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0535908-A1 Polyester/polycarbonate molding compositions GENERAL ELECTRIC COMPANY (US) 1993-04-07 EP disclosed
EP-0520806-A2 Optical polycarbonate compositions GE PLASTICS JAPAN LIMITED (JP) 1992-12-30 EP disclosed
EP-0520804-A2 Copolymeric polycarbonate production method GE PLASTICS JAPAN LIMITED (JP) 1992-12-30 EP disclosed
US-4548987-A CONTAINING AN UNSATURATED KETONE ESTER BAYER AKTIENGESELLSCHAFT (DE) 1985-10-22 US disclosed