SCHEMBL2143217

SCHEMBL2143217

CC(C)(CC(CC(C)(C)c1ccc(O)cc1)c1ccc(O)cc1)c1ccc(O)cc1.Oc1ccc(-c2cc(-c3ccc(O)cc3)cc(-c3ccc(O)cc3)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 10/20 0.47
SHBG P04278 1/20 0.46
ESR2 Q92731 7/20 0.44
KIF11 P52732 1/20 0.40
ABL1 P00519 3/20 0.39
ABCB1 P08183 3/20 0.39
BCR P11274 3/20 0.39
LMNA P02545 2/20 0.39
CYP3A4 P08684 2/20 0.39
AR P10275 2/20 0.39
SLC6A2 P23975 2/20 0.39
SLC6A3 Q01959 2/20 0.39
TYR P14679 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
SLC6A4 P31645 1/20 0.39
HTR6 P50406 1/20 0.39
ESRRG P62508 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5140991 0.78 SHBG (0.45) ESR1SHBGESR2KIF11ABL1
SCHEMBL3480352 0.75 SHBG (0.52) ESR1SHBGESR2LMNACYP3A4
SCHEMBL8625814 0.75 SHBG (0.39) ESR1SHBGESR2CYP3A4CYP2C9
SCHEMBL9244771 0.74 SHBG (0.51) ESR1SHBGESR2LMNACYP3A4
SCHEMBL7174944 0.74 ESR1 (0.73) ESR1SHBGESR2KIF11ABL1
SCHEMBL5604262 0.74 ESR1 (0.64) ESR1SHBGESR2KIF11ABL1
SCHEMBL28222983 0.72 SHBG (0.57) ESR1SHBGESR2KIF11LMNA
SCHEMBL647964 0.71 SHBG (0.88) ESR1SHBGESR2KIF11LMNA
SCHEMBL16581467 0.70 ESR1 (0.64) ESR1ESR2KIF11ABL1ABCB1
SCHEMBL6400170 0.70 ESR1 (0.64) ESR1ESR2KIF11ABL1ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1860374-B1 LIGHT GUIDING PLATE FORMED OF TRANSPARENT RESIN, PLANAR LIGHT SOURCE, AND LIGHT GUIDING PLATE MANUFACTURING METHOD MITSUBISHI GAS CHEMICAL CO (JP) 2012-04-25 EP disclosed
US-7616858-B2 Light guiding plate made of transparent resin, surface-emitting light source apparatus and process for manufacturing light guiding plate MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2009-11-10 US disclosed
US-20080144324-A1 Light Guiding Plate Made of Transparent Resin, Surface-Emitting Light Source Apparatus and Process For Manufacturing Light Guiding Plate MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2008-06-19 US disclosed
EP-1860374-A1 LIGHT GUIDING PLATE FORMED OF TRANSPARENT RESIN, PLANAR LIGHT SOURCE, AND LIGHT GUIDING PLATE MANUFACTURING METHOD Mitsubishi Engineering-Plastics Corporation (JP) 2007-11-28 EP disclosed