Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS15 | P98073 | 3/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9252486 | 0.91 | ITGB3 (0.43) | NAMPTF10ITGB3ITGA2BHDAC1 | |
| Bromide SCHEMBL9254604 | 0.90 | ITGB3 (0.43) | NAMPTF10ITGB3ITGA2BHDAC1 | |
| SCHEMBL8863519 | 0.86 | HDAC1 (0.52) | TMPRSS15NAMPTMAPTSMN1; SMN2NPC1 | |
| SCHEMBL9251312 | 0.85 | TMPRSS15 (0.40) | TMPRSS15NAMPTF10MAPTSMN1; SMN2 | |
| SCHEMBL9250822 | 0.85 | ADORA2A (0.46) | ADORA2A | |
| Hydrochloric Acid SCHEMBL9255053 | 0.85 | HDAC1 (0.51) | TMPRSS15NAMPTMAPTSMN1; SMN2NPC1 | |
| SCHEMBL9254880 | 0.84 | CHEK2 (0.49) | TMPRSS15F10MAPTSMN1; SMN2NPC1 | |
| SCHEMBL9246065 | 0.83 | TMPRSS15 (0.39) | TMPRSS15NAMPTF10MAPTSMN1; SMN2 | |
| SCHEMBL9571166 | 0.83 | HDAC1 (0.40) | TMPRSS15NAMPTF10MAPTSMN1; SMN2 | |
| SCHEMBL9252530 | 0.80 | PTGER4 (0.51) | RIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |
| EP-0531883-A1 | Condensed 5-membered ring heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |