Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 4/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | AKT2 | P31751 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | BLK | P51451 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254321 | 0.93 | CALM1 (0.47) | CALM1ESR1 | |
| SCHEMBL11658632 | 0.81 | SLC2A1 (0.46) | SMPD1CALM1CHUKDAPK3JAK2 | |
| SCHEMBL10899758 | 0.79 | ALDH1A1 (0.43) | CALM1CHUKDAPK3JAK2ROCK2 | |
| SCHEMBL14495326 | 0.79 | CALM1 (0.50) | CALM1ALDH1A1HPGD | |
| SCHEMBL11315398 | 0.79 | LMNA (0.53) | SMPD1ALDH1A1HPGDPTPN11S1PR3 | |
| SCHEMBL28319408 | 0.78 | PTPN11 (0.55) | SMPD1CHUKDAPK3JAK2ROCK2 | |
| SCHEMBL2856448 | 0.78 | PTPN11 (0.55) | SMPD1CHUKDAPK3JAK2ROCK2 | |
| SCHEMBL13957128 | 0.78 | PTPN11 (0.55) | SMPD1CHUKDAPK3JAK2ROCK2 | |
| SCHEMBL1776071 | 0.78 | PTPN11 (0.55) | SMPD1CHUKDAPK3JAK2ROCK2 | |
| SCHEMBL24866002 | 0.78 | SMPD1 (0.41) | SMPD1CALM1CHUKDAPK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432237-A | Radically polymerizable composition | SHOWA DENKO K.K. (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0399463-B1 | Radically polymerizable composition | SHOWA DENKO KK (JP) | 1994-02-23 | — | — | EP | disclosed |
| EP-0399463-A2 | Radically polymerizable composition | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1990-11-28 | — | — | EP | disclosed |