Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 4/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | FDPS | P14324 | 3/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | BLK | P51451 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30867116 | 1.00 | SMPD1 (0.41) | SMPD1ESR1FDPSCALM1CHUK | |
| SCHEMBL9250450 | 0.78 | SMPD1 (0.43) | SMPD1ESR1CALM1CHUKDAPK3 | |
| SCHEMBL7354913 | 0.77 | PDE4D (0.41) | SMPD1CALM1PPARG | |
| SCHEMBL10896158 | 0.75 | ALDH1A1 (0.44) | SMPD1CHUKDAPK3JAK2ROCK2 | |
| SCHEMBL17832225 | 0.75 | PPARG (0.55) | FDPSTHRATHRBPPARG | |
| SCHEMBL16606362 | 0.75 | CYP3A4 (0.51) | FDPSCALM1PPARG | |
| SCHEMBL9254321 | 0.74 | CALM1 (0.47) | ESR1FDPSCALM1 | |
| SCHEMBL14495326 | 0.74 | CALM1 (0.50) | CALM1ALDH1A1HPGD | |
| SCHEMBL18994187 | 0.74 | FDPS (0.50) | SMPD1FDPSTHRATHRBPPARG | |
| SCHEMBL11315398 | 0.74 | LMNA (0.53) | SMPD1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240327444-A1 | Method for Purifying Nucleotides, Device for Purifying Nucleotides, Hy-Drophobic Reagent, and Hydrophobic Substrate | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2024-10-03 | — | — | US | disclosed |
| EP-4368628-A1 | METHOD FOR PURIFYING NUCLEOTIDES, DEVICE FOR PURIFYING NUCLEOTIDES, HYDROPHOBIC REAGENT, AND HYDROPHOBIC SUBSTRATE | Japan Science and Technology Agency (JP) | 2024-05-15 | — | — | EP | disclosed |
| WO-2023282245-A1 | METHOD FOR PURIFYING NUCLEOTIDES, DEVICE FOR PURIFYING NUCLEOTIDES, HYDROPHOBIC REAGENT, AND HYDROPHOBIC SUBSTRATE | 国立研究開発法人科学技術振興機構 | 2023-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240327444-A1 | Method for Purifying Nucleotides, Device for Purifying Nucleotides, Hy-Drophobic Reagent, and Hydrophobic Substrate | NUDT1, SAMHD1, PNP | SMPD1 1013/4885ESR1 4281/4885FDPS 661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.