Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | ESRRG | P62508 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11834731 | 0.85 | SHBG (0.33) | SHBG | |
| SCHEMBL8625811 | 0.83 | ESR1 (0.34) | ESR1ESR2SHBGMIFCYP3A4 | |
| SCHEMBL6157069 | 0.79 | SHBG (0.50) | ESR1ESR2SHBGRORCMIF | |
| SCHEMBL18139 | 0.79 | SHBG (0.53) | ESR1ESR2SHBGMIFLMNA | |
| SCHEMBL5140991 | 0.75 | SHBG (0.45) | ESR1ESR2SHBGMIFLMNA | |
| SCHEMBL9473539 | 0.71 | — | — | |
| SCHEMBL20718388 | 0.70 | ESR1 (0.60) | ESR1ESR2MIFSLC28A3LMNA | |
| SCHEMBL3480352 | 0.70 | SHBG (0.52) | ESR1ESR2SHBGMIFLMNA | |
| SCHEMBL9508102 | 0.70 | ESR1 (0.56) | ESR1ESR2CYP3A4SLC6A2 | |
| SCHEMBL15893491 | 0.69 | ESR1 (0.46) | ESR1ESR2MIFLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382605-A | Polyesters and/or polycarbonates for articles for medical equipment or moldings | MILES INC. (US) | 1995-01-17 | — | — | US | disclosed |
| EP-0572889-A1 | Polycondensate composition stabilised against ionising-radiation induced degradation | Bayer Corporation (US) | 1993-12-08 | — | — | EP | disclosed |