Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MLNR | O43193 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4553089 | 0.86 | PTGS2 (0.67) | HCRTR1ALDH1A1MAPTPTGS2TSHR | |
| SCHEMBL9084521 | 0.83 | HCRTR1 (0.59) | HCRTR1ALDH1A1PTGS2TSHRHSD17B10 | |
| SCHEMBL11327533 | 0.83 | NAAA (0.63) | HCRTR1ALDH1A1PTGS2TSHRMEN1 | |
| SCHEMBL23220252 | 0.81 | ALDH1A1 (0.70) | HCRTR1ALDH1A1PTGS2TSHRHSD17B10 | |
| SCHEMBL29234670 | 0.81 | ALDH1A1 (0.70) | HCRTR1ALDH1A1PTGS2TSHRHSD17B10 | |
| SCHEMBL5943342 | 0.80 | HCRTR1 (0.58) | HCRTR1ALDH1A1PTGS2TSHRHSD17B10 | |
| SCHEMBL9545778 | 0.80 | PTGS2 (0.62) | HCRTR1ALDH1A1MAPTPTGS2TSHR | |
| SCHEMBL11319199 | 0.79 | PTGS2 (0.76) | ALDH1A1MAPTPTGS2TSHRHSD17B10 | |
| SCHEMBL4954820 | 0.79 | HCRTR1 (0.54) | HCRTR1ALDH1A1PTGS2TSHRHSD17B10 | |
| SCHEMBL3864610 | 0.78 | MEN1 (0.68) | HCRTR1ALDH1A1PTGS2TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540544-B1 | BENZOIC ACID SUBSTITUTED DERIVATIVES HAVING CARDIOVASCULAR ACTIVITY | ITALFARMACO SPA (IT) | 1995-02-15 | — | — | EP | claimed |
| US-5366992-A | IN MIXTURE WITH AN EXCIPIENT | ITALFARMACO S.P.A. (IT) | 1994-11-22 | — | — | US | claimed |