Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | ROS1 | P08922 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7287307 | 0.85 | CA1 (0.45) | PRKCZCA1CA2CA9CYP3A4 | |
| SCHEMBL1401395 | 0.81 | CA1 (0.44) | PRKCZCA1CA2CA9MRGPRX4 | |
| SCHEMBL9250998 | 0.80 | PRKCZ (0.37) | MAPTPRKCZCA1CA2CA9 | |
| SCHEMBL8736474 | 0.77 | L3MBTL1 (0.47) | MAPTCA1CA2CA9CYP3A4 | |
| SCHEMBL9251005 | 0.75 | PRKCZ (0.38) | MAPTPRKCZCA1CA2CA9 | |
| SCHEMBL3933703 | 0.71 | IKBKB (0.46) | MAPTPRKCZCA1CA2CA9 | |
| SCHEMBL16863083 | 0.69 | CA1 (0.47) | CA1CA2CA9 | |
| SCHEMBL4056753 | 0.69 | CA1 (0.51) | CA1CA2CA9 | |
| SCHEMBL3999022 | 0.67 | KCNH2 (0.45) | PRKCZROCK1IKBKB | |
| SCHEMBL31719936 | 0.67 | CYP17A1 (0.49) | MAPTPRKCZMRGPRX4IKBKBPORCN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5455348-A | Anticoagulants | Thomae, Karl (DE) | 1995-10-03 | — | — | US | disclosed |