Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | ROS1 | P08922 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | PRKX | P51817 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7287307 | 0.77 | CA1 (0.45) | PRKCZCYP3A4ROCK1IKBKBCA1 | |
| SCHEMBL9250996 | 0.75 | MAPT (0.38) | PRKCZCYP3A4ROCK1ROCK2DYRK3 | |
| SCHEMBL1401395 | 0.73 | CA1 (0.44) | PRKCZIKBKBCA1CA2CA9 | |
| SCHEMBL9250998 | 0.72 | PRKCZ (0.37) | PRKCZCYP3A4ROCK1ROCK2DYRK3 | |
| SCHEMBL3933703 | 0.72 | IKBKB (0.46) | PRKCZCYP3A4ROCK1ROCK2DYRK3 | |
| SCHEMBL30050418 | 0.67 | CYP11B2 (0.60) | CYP3A4CYP19A1MAPT | |
| SCHEMBL1204577 | 0.67 | CYP11B2 (0.60) | CYP3A4CYP19A1MAPT | |
| SCHEMBL31588898 | 0.66 | CACNA2D1 (0.47) | PRKCZCYP3A4ROCK1ROCK2IKBKB | |
| SCHEMBL21178930 | 0.66 | PRKCZ (0.44) | PRKCZCYP3A4ROCK1IKBKBIMPDH2 | |
| SCHEMBL19476153 | 0.66 | NAMPT (0.53) | CYP3A4ROCK1ROCK2IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5455348-A | Anticoagulants | Thomae, Karl (DE) | 1995-10-03 | — | — | US | disclosed |