Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251008 | 0.91 | IDO1 (0.43) | CHRM5IDO1TDO2SLC6A2SLC6A4 | |
| SCHEMBL9256092 | 0.79 | SLC6A2 (0.40) | ACHEADRA2AADRA2BADRA2CHTR2C | |
| SCHEMBL9253636 | 0.75 | OPRL1 (0.38) | ADRA2AIDO1TDO2SLC6A2SLC6A4 | |
| SCHEMBL9257472 | 0.75 | MCOLN2 (0.36) | IDO1TDO2CHRNB4CHRNA3ALDH1A1 | |
| SCHEMBL9251016 | 0.72 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL9256621 | 0.72 | IDO1 (0.51) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL2093016 | 0.71 | CA12 (0.48) | CA1CA2CA12CA4CA7 | |
| SCHEMBL577967 | 0.71 | HTR2C (0.64) | HTR2CSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3126948 | 0.71 | HTR1A (0.43) | ADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL23848197 | 0.71 | SLC6A2 (0.50) | HTR2CCHRNB4CHRNA3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |