Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257882 | 0.94 | ALDH1A1 (0.41) | ALDH1A1KDM1AMEN1KMT2A | |
| SCHEMBL4674804 | 0.85 | IDO1 (0.39) | OPRD1MGLL | |
| SCHEMBL9668878 | 0.82 | OPRD1 (0.40) | OPRM1OPRD1OPRK1OPRL1TACR1 | |
| SCHEMBL11610656 | 0.81 | OPRD1 (0.53) | OPRD1 | |
| SCHEMBL9251008 | 0.80 | IDO1 (0.43) | OPRM1OPRD1OPRK1OPRL1TACR1 | |
| SCHEMBL9256629 | 0.79 | DRD3 (0.51) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL9253506 | 0.79 | IDO1 (0.41) | OPRM1OPRD1OPRK1OPRL1MEN1 | |
| SCHEMBL9253016 | 0.79 | MRGPRX1 (0.40) | TACR1 | |
| SCHEMBL11401169 | 0.77 | OPRM1 (0.46) | OPRM1OPRD1OPRK1OPRL1TACR1 | |
| SCHEMBL5491850 | 0.75 | MMP1 (0.49) | OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |