Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.59 |
| ▸ | DRD3 | P35462 | 3/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.59 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.59 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.59 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.59 |
| ▸ | DRD1 | P21728 | 2/20 | 0.59 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.59 |
| ▸ | HTR2A | P28223 | 2/20 | 0.59 |
| ▸ | HRH1 | P35367 | 2/20 | 0.59 |
| ▸ | HTR2B | P41595 | 2/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.57 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12373318 | 0.89 | DRD3 (0.59) | OPRM1DRD3CHRM2CHRM4CHRM5 | |
| SCHEMBL8371748 | 0.81 | OPRD1 (0.67) | OPRM1DRD3CHRM2CHRM4CHRM5 | |
| SCHEMBL10725953 | 0.81 | LMNA (0.57) | OPRM1DRD3CHRM2CHRM4CHRM5 | |
| SCHEMBL5578085 | 0.80 | DPP7 (0.65) | OPRM1DRD3CHRM2CHRM4CHRM5 | |
| SCHEMBL10725956 | 0.80 | LMNA (0.56) | OPRM1DRD3CHRM2CHRM4CHRM5 | |
| SCHEMBL11938950 | 0.79 | OPRM1 (0.68) | OPRM1DRD3CHRM2CHRM4CHRM5 | |
| SCHEMBL172597 | 0.79 | KMT2A (0.62) | OPRM1DRD3CHRM2CHRM4CHRM5 | |
| SCHEMBL6163175 | 0.78 | DRD2 (0.59) | OPRM1DRD3HTR2ALMNAOPRD1 | |
| SCHEMBL4249388 | 0.78 | LMNA (0.60) | OPRM1DRD3CHRM2CHRM4CHRM5 | |
| SCHEMBL7963339 | 0.78 | DRD3 (0.59) | OPRM1DRD3CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| CN-1058780-A | Has the active thiazolidine carboxylic acid amides derivative of anti-allergy, their preparation and application | SANKYO CO (JP) | 1992-02-19 | — | — | CN | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |