Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 10/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311411 | 0.94 | AGTR1 (0.41) | MMP8AGTR1AGTR2LTB4R2ABCB11 | |
| SCHEMBL8315967 | 0.90 | AGTR1 (0.40) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL9254418 | 0.81 | PPARG (0.35) | AGTR1 | |
| SCHEMBL9487766 | 0.77 | AGTR1 (0.46) | AGTR1AGTR2LTB4R2ABCB11GP6 | |
| SCHEMBL9709552 | 0.76 | IAPP (0.40) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL1370358 | 0.76 | MME (0.47) | MMP8 | |
| SCHEMBL27962068 | 0.76 | MME (0.47) | MMP8 | |
| SCHEMBL840644 | 0.75 | AGTR1 (0.35) | AGTR1AGTR2LTB4R2ABCB11GP6 | |
| SCHEMBL840643 | 0.75 | AGTR1 (0.37) | AGTR1AGTR2LTB4R2ABCB11GP6 | |
| SCHEMBL9488684 | 0.75 | AGTR1 (0.58) | AGTR1LTB4R2ABCB11GP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389632-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1995-02-14 | — | — | US | disclosed |
| US-5387747-A | Used in the treatment and prevention of cardiovascular diseases: hypertension, cardiac insufficiency and atherosclerosis | LABORATOIRES UPSA (FR) | 1995-02-07 | — | — | US | disclosed |