Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 7/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.38 |
| ▸ | BRS3 | P32247 | 5/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251535 | 0.90 | MMP8 (0.39) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL9254418 | 0.84 | PPARG (0.35) | AGTR1BRS3PPARAPPARG | |
| SCHEMBL7311411 | 0.84 | AGTR1 (0.41) | AGTR1LTB4R2ABCB11GP6BRS3 | |
| SCHEMBL9489773 | 0.80 | AGTR1 (0.58) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL9488684 | 0.80 | AGTR1 (0.58) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL9709552 | 0.80 | IAPP (0.40) | AGTR1LTB4R2BRS3 | |
| SCHEMBL840644 | 0.79 | AGTR1 (0.35) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL7271536 | 0.79 | AGTR1 (0.62) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL7271546 | 0.79 | AGTR1 (0.62) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL840643 | 0.79 | AGTR1 (0.37) | AGTR1LTB4R2ABCB11GP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0628046-B1 | TRIAZOLOPYRIMIDIN DERIVATIVES AS ANTIOTENSIN II RECEPTOR ANTAGONISTS | UNION PHARMA SCIENT APPL (FR) | 1999-05-12 | — | — | EP | disclosed |
| WO-1993017024-A1 | TRIAZOLOPYRIMIDIN DERIVATIVES AS ANTIOTENSIN II RECEPTOR ANTAGONISTS | LABORATOIRES UPSA (FR) | 1993-09-02 | — | — | WO | disclosed |