Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.35 |
| ▸ | BRS3 | P32247 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315967 | 0.84 | AGTR1 (0.40) | PPARGPPARAAGTR1BRS3 | |
| SCHEMBL19222672 | 0.83 | S1PR1 (0.39) | — | |
| SCHEMBL9251535 | 0.81 | MMP8 (0.39) | AGTR1 | |
| SCHEMBL1773521 | 0.80 | FYN (0.39) | AGTR1 | |
| SCHEMBL12600305 | 0.79 | AGTR1 (0.35) | AGTR1 | |
| SCHEMBL7311411 | 0.79 | AGTR1 (0.41) | AGTR1BRS3 | |
| SCHEMBL7355960 | 0.79 | MMP2 (0.35) | PPARGPPARAAGTR1BRS3 | |
| SCHEMBL6955822 | 0.78 | TP53 (0.41) | AGTR1 | |
| SCHEMBL6962635 | 0.78 | AKT1 (0.36) | AGTR1 | |
| SCHEMBL6956494 | 0.77 | TDP1 (0.40) | BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389632-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1995-02-14 | — | — | US | disclosed |
| US-5387747-A | Used in the treatment and prevention of cardiovascular diseases: hypertension, cardiac insufficiency and atherosclerosis | LABORATOIRES UPSA (FR) | 1995-02-07 | — | — | US | disclosed |