Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | CSF1R | P07333 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | DHFR | P00374 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9249886 | 0.83 | MEN1 (0.39) | ALDH1A1TSHRL3MBTL1MAPTCRHBP | |
| SCHEMBL9249935 | 0.83 | NR3C2 (0.38) | NR3C2ALDH1A1TSHRGLAMAPT | |
| SCHEMBL11521967 | 0.82 | ALDH1A3 (0.45) | ALDH1A1TSHRL3MBTL1MAPTKDM4E | |
| SCHEMBL9252467 | 0.79 | TOP2A (0.42) | EGFRALDH1A1TDP1 | |
| SCHEMBL9101634 | 0.79 | TDP1 (0.37) | ALDH1A1TSHRL3MBTL1MAPTNPSR1 | |
| SCHEMBL29708057 | 0.74 | CHEK1 (0.52) | ALDH1A1TSHRMAPTNPSR1KDM4E | |
| SCHEMBL346454 | 0.74 | CHEK1 (0.52) | ALDH1A1TSHRMAPTNPSR1KDM4E | |
| SCHEMBL7236844 | 0.74 | KEAP1 (0.37) | L3MBTL1TDP1ALDH1A3INSR | |
| SCHEMBL13237051 | 0.73 | CYP2A6 (0.47) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL2185816 | 0.71 | APAF1 (0.49) | APAF1CASP3CASP6SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395969-A | Charge transport or control agents; photoconductors; electrographic toners | ZENECA LIMITED (GB) | 1995-03-07 | — | — | US | disclosed |
| US-5278315-A | Phenylaminonaphthalyl hydrazone | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-11 | — | — | US | disclosed |