Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.52 |
| ▸ | NEK2 | P51955 | 1/20 | 0.52 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | RET | P07949 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | EP300 | Q09472 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.50 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29708057 | 1.00 | CHEK1 (0.52) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL13486828 | 0.88 | CA2 (0.49) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL8699190 | 0.84 | RET (0.40) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL9915625 | 0.83 | CHEK1 (0.55) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL9252467 | 0.82 | TOP2A (0.42) | RETTDP1LMNAMEN1THRB | |
| SCHEMBL9101634 | 0.82 | TDP1 (0.37) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL1275475 | 0.81 | KDM4E (0.63) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL11521967 | 0.81 | ALDH1A3 (0.45) | RETTDP1LMNAMAPTHTT | |
| SCHEMBL15267535 | 0.80 | CHEK1 (0.52) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL982388 | 0.80 | KMT2A (0.61) | TDP1LMNAHTTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 859 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11918671-B2 | Multi-tone hair dyeing method in three steps | HENKEL AG & CO. KGAA (DE) | 2024-03-05 | — | — | US | claimed |
| US-20230031764-A1 | MULTI-TONE HAIR DYEING METHOD IN THREE STEPS | HENKEL AG & CO. KGAA (DE) | 2023-02-02 | — | — | US | claimed |
| US-20220257483-A1 | INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL | HENKEL AG & CO. KGAA (DE) | 2022-08-18 | — | — | US | claimed |
| CN-114746069-A | Three-step multi-tone hair dyeing method | 汉高股份有限及两合公司 | 2022-07-12 | — | — | CN | claimed |
| EP-4003286-A1 | INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL | Henkel AG & Co. KGaA (DE) | 2022-06-01 | — | — | EP | claimed |
| CN-114173750-A | Improving the stability of agents for treating keratin materials | 汉高股份有限及两合公司 | 2022-03-11 | — | — | CN | claimed |
| WO-2021110306-A1 | MULTI-TONE HAIR DYEING METHOD IN THREE STEPS | HENKEL AG & CO. KGAA (DE) | 2021-06-10 | — | — | WO | claimed |
| WO-2021013420-A1 | INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL | HENKEL AG & CO. KGAA (DE) | 2021-01-28 | — | — | WO | claimed |
| EP-1965753-B1 | REVERSIBLY CHANGEABLE HAIR COLOR | HENKEL AG & CO KGAA (DE) | 2013-09-04 | — | — | EP | claimed |
| CN-103251513-A | Dye composition comprising at least one colorless disulfide/thiol precursor, and dyeing process using the composition | OREAL | 2013-08-21 | — | — | CN | claimed |
| EP-1194118-A1 | AGENT FOR COLORING FIBERS | Wella Aktiengesellschaft (DE) | 2002-04-10 | — | — | EP | claimed |
| WO-2002022092-A1 | HAIR DYEING AGENTS CONTAINING INDIGO DERIVATIVES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-03-21 | — | — | WO | claimed |
| WO-2001085111-A1 | AGENT FOR COLORING FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2001-11-15 | — | — | WO | claimed |
| EP-1143923-A1 | AGENT AND METHOD FOR COLOURING FIBRES | Wella Aktiengesellschaft (DE) | 2001-10-17 | — | — | EP | claimed |
| WO-2001062219-A1 | AGENT FOR DYEING FIBRES COMPRISING AN INDOLINE/INDOLIUM DERIVATIVE | WELLA AKTIENGESELLSCHAFT (DE) | 2001-08-30 | — | — | WO | claimed |
| WO-2001028507-A1 | AGENT AND METHOD FOR COLOURING FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2001-04-26 | — | — | WO | claimed |
| WO-2001013866-A1 | AGENT FOR DYING KERATIN FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-03-01 | — | — | WO | claimed |
| EP-1054657-A1 | AGENT FOR COLORING FIBERS | Wella Aktiengesellschaft (DE) | 2000-11-29 | — | — | EP | claimed |
| WO-2000033799-A1 | AGENT FOR COLORING FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2000-06-15 | — | — | WO | claimed |
| US-4148658-A | BENZOYLMETHYLENE-BENSOTHIAZOLYIDEND-THIAZOLIDONE COMPOUND, AMINE, AND AMINOARYLCARBONYL COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1979-04-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220257483-A1 | INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL | KRT18, VIM, CDH1 | CHEK1 138/4885NEK2 1917/4885LIMK1 2016/4885 |
| US-11918671-B2 | Multi-tone hair dyeing method in three steps | TYR, HAO2, HAAO | CHEK1 1961/4885NEK2 3316/4885LIMK1 3079/4885 |
| US-20230031764-A1 | MULTI-TONE HAIR DYEING METHOD IN THREE STEPS | TYR, HAO2, HAAO | CHEK1 1961/4885NEK2 3316/4885LIMK1 3079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.